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    OpenPayerBilling CodesGenetic carrier and genetic susceptibility to diseaseICD-10-CM z15-genetic-susceptibility-to-disease
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    ICD-10-CM Code For Genetic Susceptibility To Disease: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group Z15 includes diagnoses that indicate genetic susceptibility to specific diseases or carrier status for inherited disorders, such as susceptibility to malignant neoplasms, infectious diseases, and metabolic conditions. These ICD-10-CM diagnosis codes are used to document patients with a known genetic predisposition or carrier state, capturing relevant risk factors, family history implications, and need for surveillance or counseling. Accurate coding within the ICD-10-CM Z15 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM Z15: Genetic Susceptibility To Disease Overview

    This group encompasses diagnoses indicating a patient has a genetic predisposition or carrier status for specific inherited diseases rather than active disease. It targets genetic and hereditary conditions across organ systems where family or genetic history affects risk. Accurate coding is important for complete clinical documentation and can influence reimbursement and utilization of preventive services.

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    When to Use

    Use a code from this group when a clinician documents a patients genetic susceptibility, carrier status, or inherited predisposition to a particular disease without current active disease. These codes apply when genetic testing, family history, or clinical assessment identifies an elevated risk but no manifest disease is present.

    ICD-10-CM Codes

    14 rows

    ICD-10-CM CodeDescription
    Z15.01Genetic susceptibility to malignant neoplasm of breast
    Z15.02Genetic susceptibility to malignant neoplasm of ovary
    Z15.03Genetic susceptibility to malignant neoplasm of prostate
    Z15.04Genetic susceptibility to malignant neoplasm of endometrium
    Z15.05Genetic susceptibility to malignant neoplasm of fallopian tube(s)
    Z15.060Genetic susceptibility to colorectal cancer
    Z15.068Genetic susceptibility to other malignant neoplasm of digestive system
    Z15.07Genetic susceptibility to malignant neoplasm of urinary tract
    Z15.09Genetic susceptibility to other malignant neoplasm
    Z15.1Genetic susceptibility to epilepsy and neurodevelopmental disorders
    Z15.2Genetic susceptibility to obesity
    Z15.3Genetic susceptibility to kidney disease
    Z15.81Genetic susceptibility to multiple endocrine neoplasia [MEN]
    Z15.89Genetic susceptibility to other disease

    DRG Codes

    1 rows

    DRG CodeDescription
    951Other Factors Influencing Health Status

    Related Codes

    Z14-GENETIC-CARRIER

    ICD-10-CM Code For Genetic Carrier: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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