ICD-10-PCS Code For Extracorporeal: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XY0Y includes procedures performed to introduce therapeutic, diagnostic, nutritional, physiological, or prophylactic substances or devices in extracorporeal systems. These ICD-10-PCS codes are used for inpatient documentation when extracorporeal introduction techniques are employed to deliver or connect substances or devices outside the body. Accurate coding within the ICD-10-PCS XY0Y group is essential for proper inpatient reimbursement, as it captures the procedure performed and supports clinical documentation accuracy.

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Extracorporeal Introduction Procedure Overview

Procedures in this group involve the introduction of therapeutic, diagnostic, nutritional, physiological, or prophylactic substances or devices using extracorporeal techniques. These procedures target the extracorporeal system and are coded in the New Technology section of the International Classification of Diseases, Tenth Revision, Procedure Coding System. Accurate coding of these introduction procedures is important for clear inpatient documentation and for appropriate inpatient reimbursement.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
Y	Body System	Extracorporeal
0	Operation	Introduction
Y	Body Part	Extracorporeal

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ICD-10-PCS Code For Extracorporeal: Procedure Code Group Overview

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Extracorporeal Introduction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
Y	Body System	Extracorporeal
0	Operation	Introduction
Y	Body Part	Extracorporeal

When to Use

Use codes from this group when an extracorporeal introduction technique is performed to deliver or connect therapeutic, diagnostic, nutritional, physiological, or prophylactic substances or devices. These codes apply for inpatient encounters where the extracorporeal introduction is the primary procedural action documented.

ICD-10-PCS Codes

2 rows

ICD-10-PCS Code	Description
XY0YX28	Extracorporeal Introduction of Taurolidine Anti-infective and Heparin Anticoagulant, New Technology Group 8
XY0YX37	Extracorporeal Introduction of Nafamostat Anticoagulant, New Technology Group 7

Typical Clinical Scenarios

An adult intensive care patient on prolonged extracorporeal membrane oxygenation (ECMO) develops bloodstream colonization risk and requires antimicrobial lock therapy delivered through the extracorporeal circuit to reduce infection risk while maintaining anticoagulation; the procedure is performed in the inpatient setting to introduce the combined anti-infective and anticoagulant into the extracorporeal circuit. Typical codes: XY0YX28
A postoperative patient with acute respiratory failure is placed on an extracorporeal support circuit and, due to high clotting tendency, requires initiation of a specific synthetic serine protease anticoagulant administered into the extracorporeal system to prevent circuit thrombosis during the inpatient stay. Typical codes: XY0YX37
A patient on long-term extracorporeal support develops catheter-related infection concerns despite prior measures; clinicians elect to instill an anti-infective with concurrent anticoagulant into the external circuit as part of a revised extracorporeal management plan while admitted for observation and therapy adjustment. Typical codes: XY0YX28

Related Codes

XY0V-VEIN-GRAFT-INTRODUCTION

ICD-10-PCS Code For Vein Graft: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

2 rows

ICD-10-PCS Code	Description
XY0YX28	Extracorporeal Introduction of Taurolidine Anti-infective and Heparin Anticoagulant, New Technology Group 8
XY0YX37	Extracorporeal Introduction of Nafamostat Anticoagulant, New Technology Group 7

Typical Clinical Scenarios

An adult intensive care patient on prolonged extracorporeal membrane oxygenation (ECMO) develops bloodstream colonization risk and requires antimicrobial lock therapy delivered through the extracorporeal circuit to reduce infection risk while maintaining anticoagulation; the procedure is performed in the inpatient setting to introduce the combined anti-infective and anticoagulant into the extracorporeal circuit. Typical codes: XY0YX28
A postoperative patient with acute respiratory failure is placed on an extracorporeal support circuit and, due to high clotting tendency, requires initiation of a specific synthetic serine protease anticoagulant administered into the extracorporeal system to prevent circuit thrombosis during the inpatient stay. Typical codes: XY0YX37
A patient on long-term extracorporeal support develops catheter-related infection concerns despite prior measures; clinicians elect to instill an anti-infective with concurrent anticoagulant into the external circuit as part of a revised extracorporeal management plan while admitted for observation and therapy adjustment. Typical codes: XY0YX28

Related Codes

XY0V-VEIN-GRAFT-INTRODUCTION

ICD-10-PCS Code For Vein Graft: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Extracorporeal: Procedure Code Group Overview

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Extracorporeal Introduction Procedure Overview

Code Attributes

ICD-10-PCS Code For Extracorporeal: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Extracorporeal: Procedure Code Group Overview policy alerts

Extracorporeal Introduction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in the ICD-10-PCS code group XY0Y?

Which section, body system, and operation attributes define the XY0Y group?

What are example codes in the XY0Y group and what do they represent?

When should clinicians and coders use XY0Y codes in inpatient documentation?

How does accurate coding of XY0Y procedures affect billing and reimbursement?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in the ICD-10-PCS code group XY0Y?

Which section, body system, and operation attributes define the XY0Y group?

What are example codes in the XY0Y group and what do they represent?

When should clinicians and coders use XY0Y codes in inpatient documentation?

How does accurate coding of XY0Y procedures affect billing and reimbursement?

References