ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group X2R5 includes procedures performed to replace arteries in the upper extremity. These ICD-10-PCS codes are used for inpatient documentation when an open replacement of the right upper extremity artery is performed using a bioengineered human acellular vessel as a new technology device. Accurate coding within the ICD-10-PCS X2R5 group is essential for proper inpatient reimbursement, as it captures the procedure performed and determines appropriate case mix and payment.

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Upper Extremity Artery Replacement Procedure Overview

Procedures in this ICD-10-PCS group involve replacement of the right upper extremity artery using a bioengineered conduit and are performed on the cardiovascular system. These open approach replacements restore arterial continuity or function in the right upper extremity when native vessels are diseased, damaged, or unsuitable for repair. Accurate coding is important for inpatient reimbursement because it reflects the complexity of the operation, informs case mix designation, and supports clinical documentation quality.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
2	Body System	Cardiovascular System
R	Operation	Replacement
5	Body Part	Upper Extremity Artery, Right

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ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

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Upper Extremity Artery Replacement Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
2	Body System	Cardiovascular System
R	Operation	Replacement
5	Body Part	Upper Extremity Artery, Right

When to Use

Use a code from this group when an open surgical replacement of the right upper extremity artery is performed with a bioengineered human acellular vessel. These codes apply when the native artery is replaced due to disease, injury, or insufficiency and the procedure is documented in the inpatient record.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
X2R50WA	Replacement of Right Upper Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10

DRG Codes

6 rows

DRG Code	Description
252	Other Vascular Procedures with MCC
253	Other Vascular Procedures with CC
254	Other Vascular Procedures without CC/MCC
907	Other O.R. Procedures for Injuries with MCC
908	Other O.R. Procedures for Injuries with CC
909	Other O.R. Procedures for Injuries without CC/MCC

Typical Clinical Scenarios

A 68-year-old man with progressive right hand claudication, coolness, and nonhealing fingertip ulcers due to chronic atherosclerotic occlusive disease of the right brachial and radial arteries is admitted electively after imaging shows an irreparable segment of the right upper extremity artery; open surgical replacement with a bioengineered human acellular vessel is chosen to restore distal perfusion and salvage the limb. Typical codes: X2R50WA
A 45-year-old woman presents to the emergency department with a traumatic segmental transection of the right upper extremity artery from a penetrating injury; she is taken urgently to the operating room for open arterial reconstruction and the damaged arterial segment is replaced using a bioengineered human acellular vessel to reestablish blood flow to the right hand. Typical codes: X2R50WA
A 72-year-old patient with a previously placed synthetic graft to the right upper extremity artery develops graft infection and graft failure with recurrent ischemic symptoms; inpatient management includes removal of the infected graft and open replacement of the right upper extremity artery with a bioengineered human acellular vessel to provide a biologic conduit and reduce reinfection risk. Typical codes: X2R50WA

Related Codes

X2R6-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

X2R7-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

X2R8-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

X2RJ-TRICUSPID-VALVE-REPLACEMENT

ICD-10-PCS Code For Tricuspid Valve: Procedure Code Group Overview

X2RX-THORACIC-AORTA-ARCH-REPLACEMENT

ICD-10-PCS Code For Thoracic Aorta, Arch: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
X2R50WA	Replacement of Right Upper Extremity Artery using Bioengineered Human Acellular Vessel, Open Approach, New Technology Group 10

DRG Codes

6 rows

DRG Code	Description
252	Other Vascular Procedures with MCC
253	Other Vascular Procedures with CC
254	Other Vascular Procedures without CC/MCC
907	Other O.R. Procedures for Injuries with MCC
908	Other O.R. Procedures for Injuries with CC
909	Other O.R. Procedures for Injuries without CC/MCC

Typical Clinical Scenarios

A 68-year-old man with progressive right hand claudication, coolness, and nonhealing fingertip ulcers due to chronic atherosclerotic occlusive disease of the right brachial and radial arteries is admitted electively after imaging shows an irreparable segment of the right upper extremity artery; open surgical replacement with a bioengineered human acellular vessel is chosen to restore distal perfusion and salvage the limb. Typical codes: X2R50WA
A 45-year-old woman presents to the emergency department with a traumatic segmental transection of the right upper extremity artery from a penetrating injury; she is taken urgently to the operating room for open arterial reconstruction and the damaged arterial segment is replaced using a bioengineered human acellular vessel to reestablish blood flow to the right hand. Typical codes: X2R50WA
A 72-year-old patient with a previously placed synthetic graft to the right upper extremity artery develops graft infection and graft failure with recurrent ischemic symptoms; inpatient management includes removal of the infected graft and open replacement of the right upper extremity artery with a bioengineered human acellular vessel to provide a biologic conduit and reduce reinfection risk. Typical codes: X2R50WA

Related Codes

X2R6-LEFT-UPPER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Upper Extremity: Procedure Code Group Overview

X2R7-RIGHT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Right Lower Extremity: Procedure Code Group Overview

X2R8-LEFT-LOWER-EXTREMITY-REPLACEMENT

ICD-10-PCS Code For Left Lower Extremity: Procedure Code Group Overview

X2RJ-TRICUSPID-VALVE-REPLACEMENT

ICD-10-PCS Code For Tricuspid Valve: Procedure Code Group Overview

X2RX-THORACIC-AORTA-ARCH-REPLACEMENT

ICD-10-PCS Code For Thoracic Aorta, Arch: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview policy alerts

Upper Extremity Artery Replacement Procedure Overview

Code Attributes

ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Right Upper Extremity: Procedure Code Group Overview policy alerts

Upper Extremity Artery Replacement Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which primary procedure is captured by the ICD-10-PCS code group X2R5?

What is the specific ICD-10-PCS code listed for this procedure group?

What body system and operation are represented by the X2R5 code group?

Why is accurate coding within the X2R5 group important for inpatient care documentation?

Which DRG categories may be related when coding procedures in this group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which primary procedure is captured by the ICD-10-PCS code group X2R5?

What is the specific ICD-10-PCS code listed for this procedure group?

What body system and operation are represented by the X2R5 code group?

Why is accurate coding within the X2R5 group important for inpatient care documentation?

Which DRG categories may be related when coding procedures in this group?

References