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    v1.0.28
    OpenPayerBilling CodesAbnormal findings on examination of urine, without diagnosisICD-10-CM r80-proteinuria
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    ICD-10-CM Code For Proteinuria: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group R80 includes diagnoses for abnormal quantities of protein in the urine, such as albuminuria, proteinuria, and related laboratory findings indicative of renal dysfunction. These ICD-10-CM diagnosis codes are used to document detection of protein in urine specimens, capturing severity or persistence when applicable and guiding subsequent diagnostic or monitoring decisions. Accurate coding within the ICD-10-CM R80 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM R80: Proteinuria Overview

    The ICD-10-CM R80 group represents diagnoses for the presence of abnormal quantities of protein in the urine, commonly indicating renal glomerular or tubular dysfunction. These codes target the urinary system and are used when proteinuria is identified on laboratory testing without a definitive underlying renal disease diagnosis. Accurate coding matters for reimbursement because it supports appropriate claim adjudication and documents the clinical reason for further renal evaluation.

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    When to Use

    Use a code from this group when protein is detected in the urine and the provider documents this abnormal finding without a specific underlying renal diagnosis. These codes apply for single or repeated positive urinalysis results when the clinical documentation does not assign a definitive cause.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    R80.0Isolated proteinuria
    R80.1Persistent proteinuria, unspecified
    R80.2Orthostatic proteinuria, unspecified
    R80.3Bence Jones proteinuria
    R80.8Other proteinuria
    R80.9Proteinuria, unspecified

    DRG Codes

    5 rows

    DRG CodeDescription
    695Kidney and Urinary Tract Signs and Symptoms with MCC
    696Kidney and Urinary Tract Signs and Symptoms without MCC
    698Other Kidney and Urinary Tract Diagnoses with MCC
    699Other Kidney and Urinary Tract Diagnoses with CC
    700Other Kidney and Urinary Tract Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to primary care for evaluation of persistent lower limb edema and routine labs show 24-hour urine protein of 4.2 g and serum albumin is low, suggesting nephrotic-range proteinuria; the clinician documents proteinuria after quantification and refers for nephrology workup. Typical codes: R80.3
    • A pregnant woman at 32 weeks gestation is seen urgently for new-onset hypertension and dipstick urinalysis demonstrates 2+ protein; obstetric follow-up documents proteinuria on urine testing to monitor for preeclampsia. Typical codes: R80.1, R80.9
    • An elderly patient with long-standing diabetes is seen in outpatient clinic for chronic kidney disease surveillance; routine spot urine albumin-to-creatinine ratio is persistently elevated in the microalbumin range without other acute symptoms, and the visit is coded to capture abnormal urinary protein findings. Typical codes: R80.0, R80.9

    Related Codes

    R81-GLYCOSURIA

    ICD-10-CM Code For Glycosuria: Group Overview

    R82-OTHER-AND-UNSPECIFIED-URINE-FINDINGS

    ICD-10-CM Code For Other And Unspecified Abnormal Findings In Urine: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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