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    v1.0.28
    OpenPayerBilling CodesSymptoms and signs involving the skin and subcutaneous tissueICD-10-CM r22-localized-swelling-mass-lump
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    ICD-10-CM Code For Localized Swelling Mass And Lump Of Skin And Subcutaneous Tissue: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group R22 includes localized swellings, masses, and lumps of the skin and subcutaneous tissue such as lipomas, cysts, and other palpable subcutaneous lesions that have not been classified elsewhere. These ICD-10-CM diagnosis codes are used to document clinical encounters for visible or palpable external abnormalities, capturing information about anatomic location and the presence of a localized mass or swelling. Accurate coding within the ICD-10-CM R22 group supports proper claim adjudication and complete clinical documentation and appropriate reimbursement.

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    ICD-10-CM R22: Localized Swelling, Mass And Lump Of Skin And Subcutaneous Tissue Overview

    The ICD-10-CM R22 group represents localized swellings, masses, and lumps arising in the skin and subcutaneous tissue across body regions. These codes target external palpable abnormalities rather than confirmed neoplastic or infectious diagnoses and are used when a clinician documents a localized lump or swelling. Accurate coding matters for reimbursement because it clarifies the reason for evaluation and supports appropriate claim processing and clinical record completeness.

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    When to Use

    Use a code from this group when a clinician documents a localized palpable lump, mass, or swelling of the skin or subcutaneous tissue as the reason for the encounter. These codes are appropriate when the lesion is described by location and physical findings but a definitive diagnosis such as neoplasm or infection has not been assigned in the record.

    ICD-10-CM Codes

    12 rows

    ICD-10-CM CodeDescription
    R22.0Localized swelling, mass and lump, head
    R22.1Localized swelling, mass and lump, neck
    R22.2Localized swelling, mass and lump, trunk
    R22.30Localized swelling, mass and lump, unspecified upper limb
    R22.31Localized swelling, mass and lump, right upper limb
    R22.32Localized swelling, mass and lump, left upper limb
    R22.33Localized swelling, mass and lump, upper limb, bilateral
    R22.40Localized swelling, mass and lump, unspecified lower limb
    R22.41Localized swelling, mass and lump, right lower limb
    R22.42Localized swelling, mass and lump, left lower limb
    R22.43Localized swelling, mass and lump, lower limb, bilateral
    R22.9Localized swelling, mass and lump, unspecified

    DRG Codes

    2 rows

    DRG CodeDescription
    606Minor Skin Disorders with MCC
    607Minor Skin Disorders without MCC

    Typical Clinical Scenarios

    • An adult presents to urgent care with a rapidly enlarging, tender, fluctuant area on the right anterior neck after noticing it grew over 48 hours; vital signs are stable but the mass is painful and limits neck movement. Examination suggests an acute localized subcutaneous collection versus inflamed lymph node or cyst prompting imaging or incision and drainage; a diagnosis from this group is assigned to describe the localized swelling prior to definitive etiologic coding. Typical codes: R22.1, R22.2
    • A middle-aged patient in primary care has a year-long, non-tender, movable subcutaneous lump on the left forearm that has not changed in size and is suspected to be a benign lipoma; the clinician documents monitoring and elects conservative management. Because the visit focuses on a chronic, localized, non-erythematous subcutaneous mass without systemic signs, a code from this group is used to capture the lump as the reason for the encounter. Typical codes: R22.42, R22.40
    • An elderly nursing home resident with congestive heart failure and recent anticoagulation presents with a new, diffuse, non-pitting swelling over the right thigh after a minor fall; the area is tense and enlarging, raising concern for subcutaneous hematoma complicating anticoagulation management. A code from this group is assigned to identify the localized swelling as a complicating condition to guide further evaluation and coordination of comorbid care. Typical codes: R22.31, R22.33}

    Related Codes

    R20-DISTURBANCES-OF-SKIN-SENSATION

    ICD-10-CM Code For Disturbances Of Skin Sensation: Group Overview

    R21-RASH-AND-NONSPECIFIC-SKIN-ERUPTION

    ICD-10-CM Code For Rash And Other Nonspecific Skin Eruption: Group Overview

    R23-OTHER-SKIN-CHANGES

    ICD-10-CM Code For Other Skin Changes: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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