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    OpenPayerBilling CodesInfections of the skin and subcutaneous tissueICD-10-CM l00-staphylococcal-scalded-skin-syndrome
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    ICD-10-CM Code For Staphylococcal Scalded Skin Syndrome: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group L00 includes staphylococcal scalded skin syndrome and related diagnoses that cover toxin-mediated epidermal necrolysis caused by Staphylococcus aureus leading to widespread superficial skin splitting. These ICD-10-CM diagnosis codes are used to document clinical presentations of widespread epidermal detachment, infection status, and complications such as fluid loss or secondary infection, capturing disease severity and extent of skin involvement. Accurate coding within the ICD-10-CM L00 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM L00: Staphylococcal Scalded Skin Syndrome Overview

    The diagnoses in this group represent Staphylococcal scalded skin syndrome, an acute dermatologic condition caused by toxin-producing Staphylococcus aureus that primarily affects the epidermis. These codes target skin and subcutaneous tissue infections with widespread epidermal cleavage and risk of fluid and electrolyte loss. Accurate coding matters for reimbursement because it reflects severity, resource use, and supports correct claim adjudication by payers.

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    When to Use

    Use a code from this group when the clinical record documents staphylococcal scalded skin syndrome confirmed or strongly suspected based on clinical findings and microbiologic correlation when available. Codes are selected to reflect the extent of skin involvement, associated complications, and whether the condition is a primary reason for care.

    ICD-10-CM Codes

    1 rows

    ICD-10-CM CodeDescription
    L00Staphylococcal scalded skin syndrome

    DRG Codes

    2 rows

    DRG CodeDescription
    595Major Skin Disorders with MCC
    596Major Skin Disorders without MCC

    Typical Clinical Scenarios

    • An infant aged 6 weeks is brought to the emergency department with fever, irritability, and widespread superficial blistering and desquamation predominantly around the face, neck, and diaper area. Physical exam shows flaccid bullae that easily rupture, leaving erythematous, scalded-appearing skin; the infant appears systemically ill and requires prompt supportive care and evaluation for a staphylococcal toxin-mediated process. A diagnosis from this group is assigned when clinical features are consistent with a staphylococcal scalded skin syndrome in a neonate/young infant. Typical codes: L00
    • A toddler presents to the pediatric clinic with new-onset painful skin peeling after a recent outpatient skin infection; there is diffuse superficial epidermal sloughing without mucous membrane involvement and the child is well-appearing but uncomfortable. The clinician documents characteristic Nikolsky sign positivity and attributes the presentation to an exfoliative toxin-producing Staphylococcus aureus infection, assigning a code from this group to capture the toxin-mediated dermatologic condition. Typical codes: L00
    • An adult patient hospitalized after cellulitis of the axilla develops sudden widespread epidermal detachment and erythema while on systemic antibiotics; dermatology attributes this to staphylococcal exotoxin causing generalized scalded skin changes as a complication of the primary infection. The inpatient team assigns a diagnosis from this group to indicate the acute toxin-mediated dermatologic complication of a staphylococcal skin infection. Typical codes: L00

    Related Codes

    L01-IMPETIGO

    ICD-10-CM Code For Impetigo: Group Overview

    L02-CUTANEOUS-ABSCESS-FURUNCLE-CARBUNCLE

    ICD-10-CM Code For Cutaneous Abscess, Furuncle And Carbuncle: Group Overview

    L03-CELLULITIS-AND-ACUTE-LYMPHANGITIS

    ICD-10-CM Code For Cellulitis And Acute Lymphangitis: Group Overview

    L04-ACUTE-LYMPHADENITIS

    ICD-10-CM Code For Acute Lymphadenitis: Group Overview

    L05-PILONIDAL-CYST-AND-SINUS

    ICD-10-CM Code For Pilonidal Cyst And Sinus: Group Overview

    L08-OTHER-LOCAL-INFECTIONS-OF-SKIN

    ICD-10-CM Code For Other Local Infections Of Skin And Subcutaneous Tissue: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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