ICD-10-CM Code For Other And Unspecified Noninfective Gastroenteritis And Colitis: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group K52 includes noninfective gastroenteritis and colitis diagnoses, covering inflammatory conditions of the stomach and intestines not due to infectious agents, including eosinophilic and unspecified colitides. These ICD-10-CM diagnosis codes are used to document clinical presentations of noninfective enteritis and colitis, capturing disease severity, organ involvement, and clinical complexity relevant to this group. Accurate coding within the ICD-10-CM K52 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM K52: Other And Unspecified Noninfective Gastroenteritis And Colitis Overview

The ICD-10-CM K52 group includes noninfective inflammatory conditions of the stomach and intestines characterized by gastroenteritis and colitis not caused by infection. These diagnoses target the gastrointestinal tract, including the small intestine and colon, and encompass a range of inflammatory and unspecified presentations. Accurate coding matters for proper clinical documentation and supports appropriate reimbursement and claim processing.

When to Use

Codes from this group are used when a clinician documents noninfective gastroenteritis or colitis, including eosinophilic, allergic, or unspecified inflammatory conditions of the bowel. These codes apply when infectious causes have been excluded or when documentation does not support a more specific etiology.

ICD-10-CM Codes

14 rows

ICD-10-CM Code	Description
K52.0	Gastroenteritis and colitis due to radiation
K52.1	Toxic gastroenteritis and colitis
K52.21	Food protein-induced enterocolitis syndrome
K52.22	Food protein-induced enteropathy
K52.29	Other allergic and dietetic gastroenteritis and colitis
K52.3	Indeterminate colitis
K52.81	Eosinophilic gastritis or gastroenteritis
K52.82	Eosinophilic colitis
K52.831	Collagenous colitis
K52.832	Lymphocytic colitis
K52.838	Other microscopic colitis
K52.839	Microscopic colitis, unspecified
K52.89	Other specified noninfective gastroenteritis and colitis
K52.9	Noninfective gastroenteritis and colitis, unspecified

DRG Codes

7 rows

DRG Code	Description
391	Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC
392	Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC
393	Other Digestive System Diagnoses with MCC
394	Other Digestive System Diagnoses with CC
395	Other Digestive System Diagnoses without CC/MCC
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems

Typical Clinical Scenarios

An adult presents to the emergency department with sudden onset of profuse watery diarrhea, abdominal cramping, and mild dehydration after recent use of broad‑spectrum antibiotics. Stool studies are negative for enteric pathogens and C. difficile testing is also negative; the clinician documents an acute, noninfective colitis typically attributed to medication-associated colitis, so an acute noninfective gastroenteritis/colitis code is assigned. Typical codes: K52.0, K52.21
A middle‑aged patient with a history of chronic, intermittent bloody diarrhea and crampy abdominal pain over several months is evaluated in clinic; endoscopy shows inflammation confined to the colon without evidence of infectious etiology or classic inflammatory bowel disease, and symptoms are managed with anti‑inflammatory therapy and ongoing follow‑up. Because this is a recurrent, noninfective colitis of uncertain specific cause, a chronic or recurrent noninfective enteritis/colitis code is used. Typical codes: K52.2, K52.29
An elderly nursing home resident is hospitalized for worsening feeding intolerance and low‑grade fever while receiving enteral nutrition; abdominal imaging suggests small‑bowel inflammation and the chart notes unspecified noninfective gastroenteritis as a contributing condition complicating the course of care. For inpatient documentation of a noninfective gastroenteritis or colitis as a comorbidity affecting treatment, an unspecified or other specified code from this group is assigned. Typical codes: K52.9, K52.89

Related Codes

K50-CROHNS-DISEASE-REGIONAL-ENTERITIS

ICD-10-CM Code For Crohn's Disease Regional Enteritis: Group Overview

K51-ULCERATIVE-COLITIS

ICD-10-CM Code For Ulcerative Colitis: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

14 rows

ICD-10-CM Code	Description
K52.0	Gastroenteritis and colitis due to radiation
K52.1	Toxic gastroenteritis and colitis
K52.21	Food protein-induced enterocolitis syndrome
K52.22	Food protein-induced enteropathy
K52.29	Other allergic and dietetic gastroenteritis and colitis
K52.3	Indeterminate colitis
K52.81	Eosinophilic gastritis or gastroenteritis
K52.82	Eosinophilic colitis
K52.831	Collagenous colitis
K52.832	Lymphocytic colitis
K52.838	Other microscopic colitis
K52.839	Microscopic colitis, unspecified
K52.89	Other specified noninfective gastroenteritis and colitis
K52.9	Noninfective gastroenteritis and colitis, unspecified

DRG Codes

7 rows

DRG Code	Description
391	Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders with MCC
392	Esophagitis, Gastroenteritis and Miscellaneous Digestive Disorders without MCC
393	Other Digestive System Diagnoses with MCC
394	Other Digestive System Diagnoses with CC
395	Other Digestive System Diagnoses without CC/MCC
791	Prematurity with Major Problems
793	Full Term Neonate with Major Problems

Typical Clinical Scenarios

An adult presents to the emergency department with sudden onset of profuse watery diarrhea, abdominal cramping, and mild dehydration after recent use of broad‑spectrum antibiotics. Stool studies are negative for enteric pathogens and C. difficile testing is also negative; the clinician documents an acute, noninfective colitis typically attributed to medication-associated colitis, so an acute noninfective gastroenteritis/colitis code is assigned. Typical codes: K52.0, K52.21
A middle‑aged patient with a history of chronic, intermittent bloody diarrhea and crampy abdominal pain over several months is evaluated in clinic; endoscopy shows inflammation confined to the colon without evidence of infectious etiology or classic inflammatory bowel disease, and symptoms are managed with anti‑inflammatory therapy and ongoing follow‑up. Because this is a recurrent, noninfective colitis of uncertain specific cause, a chronic or recurrent noninfective enteritis/colitis code is used. Typical codes: K52.2, K52.29
An elderly nursing home resident is hospitalized for worsening feeding intolerance and low‑grade fever while receiving enteral nutrition; abdominal imaging suggests small‑bowel inflammation and the chart notes unspecified noninfective gastroenteritis as a contributing condition complicating the course of care. For inpatient documentation of a noninfective gastroenteritis or colitis as a comorbidity affecting treatment, an unspecified or other specified code from this group is assigned. Typical codes: K52.9, K52.89

Related Codes

K50-CROHNS-DISEASE-REGIONAL-ENTERITIS

ICD-10-CM Code For Crohn's Disease Regional Enteritis: Group Overview

K51-ULCERATIVE-COLITIS

ICD-10-CM Code For Ulcerative Colitis: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Other And Unspecified Noninfective Gastroenteritis And Colitis: Group Overview

Sign up for ICD-10-CM Code For Other And Unspecified Noninfective Gastroenteritis And Colitis: Group Overview policy alerts

ICD-10-CM K52: Other And Unspecified Noninfective Gastroenteritis And Colitis Overview

ICD-10-CM Code For Other And Unspecified Noninfective Gastroenteritis And Colitis: Group Overview

Sign up for ICD-10-CM Code For Other And Unspecified Noninfective Gastroenteritis And Colitis: Group Overview policy alerts

ICD-10-CM K52: Other And Unspecified Noninfective Gastroenteritis And Colitis Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What conditions are included in the ICD-10-CM K52 group?

Which specific codes represent eosinophilic and microscopic colitis diagnoses?

How does the K52 group support reimbursement and claim processing?

What related DRGs may be associated with diagnoses from the K52 group?

Which code denotes noninfective gastroenteritis and colitis when unspecified?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What conditions are included in the ICD-10-CM K52 group?

Which specific codes represent eosinophilic and microscopic colitis diagnoses?

How does the K52 group support reimbursement and claim processing?

What related DRGs may be associated with diagnoses from the K52 group?

Which code denotes noninfective gastroenteritis and colitis when unspecified?

References