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    OpenPayerBilling CodesIschemic heart diseasesICD-10-CM i22-subsequent-myocardial-infarction
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    ICD-10-CM Code For Subsequent ST Elevation (STEMI) And Non-ST Elevation (NSTEMI) Myocardial Infarction: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group I22 includes subsequent ST elevation myocardial infarction and subsequent non-ST elevation myocardial infarction, representing acute myocardial infarctions that occur after a prior confirmed acute myocardial infarction. These ICD-10-CM diagnosis codes are used to document recurrent or subsequent infarctions, capturing timing relative to a prior event and the type of myocardial injury. Accurate coding within the ICD-10-CM I22 group supports proper claim adjudication and complete clinical documentation for appropriate reimbursement.

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    ICD-10-CM I22: Subsequent ST Elevation (STEMI) And Non-ST Elevation (NSTEMI) Myocardial Infarction Overview

    This group represents subsequent acute myocardial infarctions occurring after an initial infarction, including both ST elevation myocardial infarction and non-ST elevation myocardial infarction subtypes affecting the heart. The diagnoses target ischemic injury to myocardial tissue within the circulatory and cardiovascular system. Accurate coding matters for reflecting clinical complexity and supporting appropriate reimbursement and claims processing.

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    When to Use

    Use a code from this group when a patient experiences an acute myocardial infarction that is documented as occurring after a prior confirmed acute myocardial infarction. Select the code that reflects whether the current event is ST elevation myocardial infarction or non-ST elevation myocardial infarction and document timing relative to the previous infarction.

    ICD-10-CM Codes

    5 rows

    ICD-10-CM CodeDescription
    I22.0Subsequent ST elevation (STEMI) myocardial infarction of anterior wall
    I22.1Subsequent ST elevation (STEMI) myocardial infarction of inferior wall
    I22.2Subsequent non-ST elevation (NSTEMI) myocardial infarction
    I22.8Subsequent ST elevation (STEMI) myocardial infarction of other sites
    I22.9Subsequent ST elevation (STEMI) myocardial infarction of unspecified site

    DRG Codes

    6 rows

    DRG CodeDescription
    280Acute Myocardial Infarction, Discharged Alive with MCC
    281Acute Myocardial Infarction, Discharged Alive with CC
    282Acute Myocardial Infarction, Discharged Alive without CC/MCC
    283Acute Myocardial Infarction, Expired with MCC
    284Acute Myocardial Infarction, Expired with CC
    285Acute Myocardial Infarction, Expired without CC/MCC

    Typical Clinical Scenarios

    • An adult patient presents to the emergency department with sudden-onset severe chest pain, diaphoresis, and shortness of breath; ECG shows new ST-segment elevations in the anterior leads and cardiac enzymes are rising, but the patient had a documented recent myocardial infarction within the past 28 days affecting a different coronary territory. A diagnosis from this group is assigned to indicate a subsequent ST-elevation myocardial infarction occurring after a recent index MI. Typical codes: I22.0, I22.1
    • An elderly patient in the hospital recovering from a non-ST elevation myocardial infarction a week earlier develops recurrent chest discomfort and troponin increase without new ST elevations, with serial ECGs showing ischemic changes different from the prior event. This situation is coded as a subsequent non-ST elevation myocardial infarction to reflect a repeat ischemic event within the post-index period. Typical codes: I22.9, I22.8
    • A middle-aged patient admitted for heart failure exacerbation is found on chart review to have had a documented ST-elevation myocardial infarction two weeks prior; during the current admission they develop recurrent localized chest pain and new Q waves consistent with extension of the prior infarct. A subsequent MI code is used to indicate extension or reinfarction following the recent initial MI. Typical codes: I22.2, I22.0

    Related Codes

    I20-ANGINA-PECTORIS

    ICD-10-CM Code For Angina Pectoris: Group Overview

    I21-ACUTE-MYOCARDIAL-INFARCTION

    ICD-10-CM Code For Acute Myocardial Infarction: Group Overview

    I23-CERTAIN-CURRENT-COMPLICATIONS-FOLLOWING-MYOCARDIAL-INFARCTION

    ICD-10-CM Code For Certain Current Complications Following STEMI And NSTEMI: Group Overview

    I24-OTHER-ACUTE-ISCHEMIC-HEART-DISEASES

    ICD-10-CM Code For Other Acute Ischemic Heart Diseases: Group Overview

    I25-CHRONIC-ISCHEMIC-HEART-DISEASE

    ICD-10-CM Code For Chronic Ischemic Heart Disease: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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