Summary & Overview
HCPCS S9376: Home Infusion Hydration Therapy, 2–3 Liters/Day
HCPCS Level II code S9376 represents a per diem charge for home infusion hydration therapy administrative and professional services covering more than two liters but no more than three liters per day, including care coordination and necessary supplies and equipment. This code matters nationally as home infusion expands access to outpatient hydration management, reduces inpatient utilization for appropriate patients, and affects how payers reimburse bundled administrative and pharmacy oversight separate from drug and nursing charges. Key payers discussed in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.
Readers will learn what S9376 covers clinically and operationally, which typical sites of service it applies to, and which components are billed separately. The publication outlines national benchmarks and policy context for home infusion per diem codes, highlights payer coverage considerations and common modifier usage, and summarizes implications for billing workflows and care coordination. Where input data was not provided, the report indicates missing items such as associated taxonomies, ICD-10 mappings, and related codes. This concise overview is intended for billing managers, pharmacy providers, and policy stakeholders seeking a clear description of S9376 and its role in home infusion services.
Billing Code Overview
HCPCS Level II code S9376 describes home infusion therapy for hydration, specifically administration and coordination for more than two liters but no more than three liters per day, billed as a per diem for administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment. Drugs and nursing visits are coded separately.
Service type: Home infusion hydration therapy (per diem administrative and professional services)
Typical site of service: Patient's home or other non-acute residential setting where infusion therapy is administered
Data not available in the input for associated taxonomies, specific ICD-10 diagnoses, related codes, and service line.
Clinical & Coding Specifications
Clinical Context
A 68-year-old male with advanced congestive heart failure and poor oral intake is discharged home requiring daily intravenous hydration of 2.5 liters to maintain euvolemia and support renal perfusion. The home health clinician coordinates with a specialty pharmacy to supply IV fluids, tubing, pumps, and administration supplies. A registered nurse visits daily for IV access assessment, flow verification, and site care while the pharmacy provides medication management, dosing verification, and remote care coordination. The billing under S9376 covers the per diem administrative and professional pharmacy services, care coordination, and supplies for hydration therapy delivering more than two liters but no more than three liters per day, while the actual fluid drug charges and nursing visits are billed separately. Typical workflow: physician orders home infusion hydration with daily volume specified; specialty pharmacy accepts order, performs pre-administration checks, arranges courier delivery of fluids and supplies; home health nursing initiates and monitors infusions per protocol; pharmacy documents dispensing, provides 24/7 clinical support, and coordinates insurance authorization and billing under S9376 for the per-diem administrative and professional infusion services.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
26 | Professional component |