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    v1.0.30
    OpenPayerBilling CodesTemporary National Codes (Non-Medicare)HCPCS hcpcs-s4014-zygote-intrafallopian-transfer-complete-cycle
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    HCPCS Level II S4014: Complete Cycle Zygote Intrafallopian Transfer (ZIFT) Case Rate

    HCPCS Level II code S4014 describes a complete cycle zygote intrafallopian transfer (ZIFT) case rate, representing a bundled reproductive medicine service that includes the clinical procedures for creating and transferring a zygote into the fallopian tube; service type: assisted reproductive procedure (complete cycle); typical site of service: outpatient surgical center or hospital outpatient department where reproductive surgeries and assisted fertilization procedures are performed.

    For related coverage guidance, see recent payer policy updates: Medical Necessity Guidelines Non-Emergency Transportation, Non-Emergent Transportation Medical Policy, Non-Emergency Facility to Facility Transfers.

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    Clinical & Coding Specifications

    Clinical Context

    A 34-year-old patient with tubal factor infertility undergoes a complete cycle of zygote intrafallopian transfer (ZIFT). The reproductive endocrinology team performs controlled ovarian hyperstimulation, serial transvaginal ultrasound and serum estradiol monitoring, followed by transvaginal oocyte retrieval under monitored anesthesia care. Retrieved oocytes are fertilized in the embryology laboratory by conventional insemination or intracytoplasmic sperm injection; resulting zygotes are cultured to the pronuclear stage and transferred into the fallopian tube via laparoscopy or transcervical catheterization the same cycle. Typical workflow steps include pre-cycle evaluation and counseling, medication administration, monitoring visits, oocyte retrieval, embryology lab fertilization and zygote culture, surgical or procedural zygote transfer, and brief post-procedure recovery with follow-up pregnancy testing and early obstetric referral if pregnancy is achieved. Typical site of service is an ambulatory surgical center or hospital outpatient setting with on-site embryology laboratory capability. Typical patient scenario includes prior infertility evaluation showing proximal or distal tubal pathology or failed in vitro fertilization attempts where ZIFT is clinically indicated and the patient opts for a cycle-based case rate covering end-to-end services for that treatment episode.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    58320Surgical retrieval of oocytes from ovary, any techniquePerformed immediately prior to fertilization step in the ZIFT cycle (oocyte retrieval).
    58974Embryo transfer, intrauterineAlthough intrauterine, conceptually related; ZIFT differs by tubal placement but embryo transfer workflow parallels and may be performed in different cycles.
    49320Laparoscopy, surgical; with biopsy(s) (single or multiple)Laparoscopic access codes commonly used when ZIFT zygote transfer is performed via laparoscopy into the fallopian tube.
    76942Ultrasound, surgical, guidance for needle placementUsed when ultrasound guidance is required during retrieval or transcervical transfer steps.
    99152Moderate sedation services provided by the same physician performing a procedure (initial 15 minutes)Billed when the physician providing the ZIFT transfer or retrieval also provides moderate sedation; institution-specific billing rules apply.

    Related Modifiers

    14 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    32Modifier 32 (Mandated Services) indicates that a CPT-coded service was required by a third party—such as an insurer, school, state agency, or court. The AMA defines it as denoting services mandated…- Use Modifier 32 when a service or procedure was explicitly mandated by a third party (for example an insurer requiring a second opinion, a school requiring a sports physical, a state agency or…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    58Modifier 58 (Staged or related procedure/service by the same physician during the postoperative period) indicates that a subsequent procedure performed by the same provider during the…- Use modifier 58 when the same physician/QHP performs a procedure during the postoperative/global period of an earlier procedure and the subsequent procedure is either planned or anticipated…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Showing 1–10 of 14

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207L00000X
    363A00000X
    227900000X
    261QF0050X
    246ZI1000X
    2084A2900X
    207PS0010X

    Related ICD-10-CM Codes

    22 rows

    ICD-10-CM CodeDescription
    E28.2Polycystic ovarian syndrome
    E28.9Ovarian dysfunction, unspecified
    N70.91Salpingitis, unspecified
    N70.92Oophoritis, unspecified
    N72Inflammatory disease of cervix uteri
    N80.6Endometriosis in cutaneous scar
    N83.9Noninflammatory disorder of ovary, fallopian tube and broad ligament, unspecified
    N91.0Primary amenorrhea
    N91.2Amenorrhea, unspecified
    N97.0Female infertility associated with anovulation

    Showing 1–10 of 22

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    10 rows

    PolicyPayerEffective Date
    Medical Necessity Guidelines Non-Emergency TransportationMass General Brigham Health Plan2026-11-01
    Non-Emergent Transportation Medical PolicyHealth-New-England2026-11-01
    Non-Emergency Facility to Facility Transfershap_caresource_mi_coordinated_health2026-11-01
    Ambulance and Medical Transport Services (Ground, Air and Water) Corporate Medical Policybcbsvermont2026-10-01
    Emergency Air/Water Ambulance Services Medical GuidelineWPS Health Insurance2026-10-01
    Non-Emergent Ambulance ServicesConnectiCare2026-09-11
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01

    Related Codes

    HCPCS-LEVEL-II-S2152-SOLID-ORGAN-TRANSPLANTATION-GLOBAL-CARE

    HCPCS Level II S2152: Solid Organ Procurement and Transplantation

    HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

    HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

    HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

    HCPCS Level II S3630: Eosinophil Count, Blood, Direct

    HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

    HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

    HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

    HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

    HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

    HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

    HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

    HCPCS Level II S9024: Paranasal Sinus Ultrasound

    HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

    HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

    HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

    HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

    HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

    HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

    Showing 1–10 of 532

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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