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    v1.0.28
    OpenPayerBilling CodesTemporary National Codes (Non-Medicare)HCPCS hcpcs-s2403-fetal-extralobar-pulmonary-sequestration-repair-in-utero
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    HCPCS Level II S2403: Repair of Extralobar Pulmonary Sequestration in Fetus

    HCPCS Level II code S2403 describes a fetal surgical procedure: repair of an extralobar pulmonary sequestration performed in utero, classified as a fetal surgical intervention typically delivered in a fetal surgery or specialized maternal-fetal medicine operating room setting; this code indicates the specific procedure performed on the fetus to correct or remove an extralobar pulmonary sequestration prior to birth and is used for procedural reporting and billing in prenatal surgical care.

    For related coverage guidance, see recent payer policy updates: Fixed Wing Air Ambulance Transport, Air Ambulance, Ambulance Services (for Tennessee Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A pregnant patient at 22–28 weeks gestation is referred to a fetal surgery center after routine prenatal ultrasound identifies an extralobar pulmonary sequestration (EPS) with progressive mass effect on the fetal thorax and mediastinal shift. Fetal MRI confirms an isolated extralobar bronchopulmonary sequestration with systemic arterial supply and evidence of developing hydrops or compromised lung development. The multidisciplinary team — maternal-fetal medicine specialist, pediatric cardiothoracic surgeon with fetal surgery expertise, anesthesiologist, neonatologist, and nursing staff — evaluates the case. After counseling and informed consent, the patient is admitted for an in utero repair procedure performed in a dedicated operating room or interventional suite equipped for fetal surgery. The procedure involves maternal regional or general anesthesia, ultrasound-guided fetal positioning, surgical access to the fetus (typically fetoscopic or open hysterotomy approach based on lesion size and gestational age), identification of the sequestration and its systemic feeding vessel, and surgical ligation/resection or ablation of the anomalous vessel and sequestrated lung tissue as indicated. Post-procedure monitoring includes maternal recovery, fetal surveillance with ultrasound and fetal heart monitoring, and possible corticosteroid administration to accelerate fetal lung maturity. Delivery planning is adjusted for potential neonatal respiratory support and immediate pediatric surgical or interventional needs. Typical site of service is a tertiary care hospital with a fetal surgery program or specialized maternal-fetal medicine center. Service type is an in utero fetal surgical procedure (fetal therapeutic intervention) for repair of extralobar pulmonary sequestration in the fetus.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    59620Fetoscopy for evaluation of fetus requiring intrauterine treatment including amniotic membrane procedures (example)May be used when fetoscopic access and evaluation are performed as part of the in utero repair workflow.
    59120Emergency hysterotomy, not for fetoscopic procedure (used in select emergent open fetal procedures)Relevant when an open maternal hysterotomy is performed to access the fetus for repair.
    76937Ultrasound guidance for needle placement (e.g., fetal procedures)Used intraoperatively for ultrasound guidance of needle, trocar, or fetoscopic instrument placement.
    36556Insertion of non-tunneled centrally inserted central venous catheter, age 5 years or older — percutaneousMay be used for maternal central venous access required for prolonged anesthesia or intraoperative monitoring.
    99499Unlisted evaluation and management service (used for specialized perioperative coordination)May be used for billing perioperative or multidisciplinary coordination services not described by standard CPT codes.

    Related Modifiers

    13 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…

    Showing 1–10 of 13

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    207V00000XObstetrics & Gynecology PhysicianAn obstetrician/gynecologist possesses special knowledge, skills and professional capability in the medical and surgical care of the female reproducti…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    207XX0801XOrthopaedic Trauma PhysicianRecognized by several state medical boards as a fellowship subspecialty program of orthopaedic surgery, orthopaedic trauma surgeons deal with the eval…
    225A00000XMusic TherapistMusic therapists use music interventions to assess clients' strengths and needs, develop goals, implement services, and evaluate and document progress…
    163WP2201XAmbulatory Care Registered NurseNursing Service Providers · Registered Nurse
    103TS0200XSchool PsychologistA psychologist whose specialty is concerned with the science and practice of psychology with children, youth, families; learners of all ages; and the …

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    9 rows

    PolicyPayerEffective Date
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01
    Clinical Policy: Air AmbulanceArizona Complete Health2026-08-01
    Clinical Policy: Air AmbulanceCentene2026-08-01
    Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceAmbetter Nevada2026-08-01
    Ambulance TransportProvidence Health Plan2026-07-01

    Related Codes

    HCPCS-LEVEL-II-S2152-SOLID-ORGAN-TRANSPLANTATION-GLOBAL-CARE

    HCPCS Level II S2152: Solid Organ Procurement and Transplantation

    HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

    HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

    HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

    HCPCS Level II S3630: Eosinophil Count, Blood, Direct

    HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

    HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

    HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

    HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

    HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

    HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

    HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

    HCPCS Level II S9024: Paranasal Sinus Ultrasound

    HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

    HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

    HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

    HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

    HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

    HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

    Showing 1–10 of 532

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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