Summary & Overview
HCPCS S0182: Procarbazine Hydrochloride, Oral, 50 mg
HCPCS Level II code S0182 denotes procarbazine hydrochloride, oral, 50 mg, an oral chemotherapy agent used in certain oncology regimens. This code identifies the medication product for billing in outpatient settings, supporting accurate tracking of oral antineoplastic therapy and aligning pharmacy claims with oncology care delivery. Nationally, clear coding for oral chemotherapeutic agents matters for medication management, pharmacy reimbursement, and patient cost-sharing.
Key payers covered in this overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find context on the clinical role of procarbazine, typical sites of service where S0182 is billed, and the categories of information commonly associated with a medication product code. The publication outlines what to expect from payer coverage and billing workflows, summarizes available benchmark topics related to medication billing, and notes where input data is missing.
This summary serves clinicians, billing staff, pharmacy managers, and policy analysts seeking a concise reference for HCPCS Level II code S0182 and its use in outpatient chemotherapy billing and claims processes.
Billing Code Overview
HCPCS Level II code S0182 represents procarbazine hydrochloride, oral, 50 mg, an oral chemotherapeutic agent used in oncology treatment regimens. The service type is oral chemotherapy medication. The typical site of service for billing this code is outpatient pharmacy or outpatient infusion clinic when dispensed for oral administration or provided as part of outpatient oncology care.
Data not available in the input.
Clinical & Coding Specifications
Clinical Context
A typical patient is an adult with a diagnosis of primary central nervous system lymphoma or Hodgkin/non-Hodgkin lymphoma receiving oral chemotherapy as part of a multi-agent regimen. The medication S0182 (procarbazine hydrochloride, oral, 50 mg) is dispensed by an outpatient infusion or oncology pharmacy and administered at home according to an oncologist’s oral chemotherapy plan. Workflow includes physician order entry in the electronic medical record, oncology pharmacist verification of dose and drug interactions, patient education on dosing schedule and precautions (including dietary restrictions and avoidance of tyramine-containing foods), documentation of baseline and ongoing labs (complete blood count, liver function tests), and periodic follow-up visits to assess response and toxicity. Billing occurs to the appropriate payer for the drug supply and any associated professional services; claims frequently include modifiers to reflect billing circumstances such as outpatient administration, services unrelated to primary procedure, or unusual services.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier; standard reporting | Use when no special circumstances apply to the billed supply. |
22 |