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    v1.0.28
    OpenPayerBilling CodesTemporary National Codes (Non-Medicare)HCPCS hcpcs-s0810-photorefractive-keratectomy-prk
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    HCPCS Level II S0810: Photorefractive Keratectomy (PRK)

    HCPCS Level II code S0810 represents photorefractive keratectomy (PRK), a laser refractive surgery procedure performed on the cornea to correct vision; service type is refractive corneal surgery and the typical site of service is an ophthalmic outpatient surgical center or ambulatory surgery center where corneal laser procedures are provided.

    For related coverage guidance, see recent payer policy updates: Fixed Wing Air Ambulance Transport, Air Ambulance, Ambulance Services (for Tennessee Only).

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    Table of contents

    Progress1 / 7

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A 28-year-old otherwise healthy patient presents to an ophthalmology clinic seeking refractive correction for symptomatic myopia and mild astigmatism. After a comprehensive preoperative evaluation including manifest and cycloplegic refraction, corneal topography, pachymetry, tear-film assessment, and a discussion of risks/benefits, the surgeon determines the patient is a candidate for photorefractive keratectomy (PRK). On the day of service the procedure is performed in an ambulatory surgical center under topical anesthesia. The corneal epithelium is removed, an excimer laser ablates the anterior stroma to reshape the cornea, and a bandage contact lens is placed for epithelial healing. Postoperative workflow includes same-day discharge instructions, topical antibiotic and steroid prescriptions, scheduled follow-up visits at day 1, week 1, and month 1, and refraction at 3 months to assess final visual outcome. Typical documentation includes pre‑op evaluation, informed consent, laser parameters, epithelial removal technique, operative note, device identifiers, postoperative instructions, and follow-up visit notes.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    65710Automated or manual corneal epithelial debridement, for corneal conditions (including PRK)Describes mechanical epithelial removal often performed at the start of PRK.
    66250Keratoplasty (corneal transplant) (used for corneal surgery reference)Not typically performed with PRK but appears in corneal procedure groupings; included for coding cross-reference when subsequent corneal surgery is necessary.
    92015Determination of refractive state (refraction) with or without autorefractionPerformed preoperatively and at postoperative visits to document refractive outcome after PRK.
    99024Postoperative follow-up services, normally included in surgical package (used for global period reference)Used to reference global surgical package rules; routine post-op visits for PRK are often bundled under the global period.
    92250Fundus photography, with interpretation and reportNot routine for straightforward PRK but may be performed preoperatively in patients with retinal history.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207W00000XOphthalmology PhysicianAn ophthalmologist has the knowledge and professional skills needed to provide comprehensive eye and vision care. Ophthalmologists are medically train…
    103K00000XBehavior AnalystA behavior analyst is qualified by at least a master's degree and Behavior Analyst Certification Board certification and/or a state-issued credential …
    1835P1200XPharmacotherapy PharmacistA licensed pharmacist who has demonstrated specialized knowledge and skill in optimizing pharmacotherapeutic care of patients, by developing, implemen…
    163WW0000XWound Care Registered NurseNursing Service Providers · Registered Nurse
    146D00000XPersonal Emergency Response AttendantIndividuals that are specially trained to assist patients living at home with urgent/emergent situations. These individuals must be able to perform C…
    171WV0202XVehicle Modifications ContractorA contractor who makes modifications to private vehicles to accommodate a health condition.
    1835P2201XAmbulatory Care PharmacistA licensed pharmacist who has demonstrated specialized knowledge and skill in the provision of integrated, accessible health care services by pharmaci…
    207ZN0500XNeuropathology PhysicianA neuropathologist is expert in the diagnosis of diseases of the nervous system and skeletal muscles and functions as a consultant primarily to neurol…

    Related ICD-10-CM Codes

    18 rows

    ICD-10-CM CodeDescription
    H02.831Dermatochalasis of right upper eyelid
    H10.9Unspecified conjunctivitis
    H16.9Unspecified keratitis
    H18.10Bullous keratopathy, unspecified eye
    H18.12Bullous keratopathy, left eye
    H18.13Bullous keratopathy, bilateral
    H18.49Other corneal degeneration
    H52.11Myopia, right eye
    H52.12Myopia, left eye
    H52.13Myopia, bilateral

    Showing 1–10 of 18

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    9 rows

    PolicyPayerEffective Date
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01
    Clinical Policy: Air AmbulanceArizona Complete Health2026-08-01
    Clinical Policy: Air AmbulanceCentene2026-08-01
    Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceAmbetter Nevada2026-08-01
    Ambulance TransportProvidence Health Plan2026-07-01

    Related Codes

    HCPCS-LEVEL-II-S2152-SOLID-ORGAN-TRANSPLANTATION-GLOBAL-CARE

    HCPCS Level II S2152: Solid Organ Procurement and Transplantation

    HCPCS-LEVEL-II-S2266-INDUCED-ABORTION-29-TO-31-WEEKS

    HCPCS Level II S2266: Induced Abortion, 29 to 31 Weeks

    HCPCS-LEVEL-II-S3630-EOSINOPHIL-COUNT-BLOOD-DIRECT

    HCPCS Level II S3630: Eosinophil Count, Blood, Direct

    HCPCS-LEVEL-II-S4017-INCOMPLETE-ART-CYCLE-CANCELLED-PRIOR-TO-STIMULATION

    HCPCS Level II S4017: Incomplete Cycle — Cancelled Prior to Stimulation

    HCPCS-LEVEL-II-S8055-ULTRASOUND-GUIDANCE-MULTIFETAL-REDUCTION-TC

    HCPCS Level II S8055: Ultrasound Guidance for Multifetal Pregnancy Reduction

    HCPCS-LEVEL-II-S8940-EQUESTRIAN-HIPPOTHERAPY-PER-SESSION

    HCPCS Level II S8940: Equestrian/Hippotherapy, Per Session

    HCPCS-LEVEL-II-S9024-PARANASAL-SINUS-ULTRASOUND

    HCPCS Level II S9024: Paranasal Sinus Ultrasound

    HCPCS-LEVEL-II-S9366-HOME-TPN-1-2L-PER-DAY-HOME-INFUSION

    HCPCS Level II S9366: Home Infusion TPN, 1–2 L/day

    HCPCS-LEVEL-II-S9446-GROUP-PATIENT-EDUCATION-NON-PHYSICIAN

    HCPCS S9446: Patient Education, Non-Physician Provider, Group, Per Session

    HCPCS-LEVEL-II-S9451-EXERCISE-CLASS-NON-PHYSICIAN-SESSION

    HCPCS S9451: Exercise Classes, Non-Physician Provider, Per Session

    Showing 1–10 of 532

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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