Summary & Overview
HCPCS S0140: Saquinavir, 200 mg
HCPCS Level II code S0140 designates Saquinavir, 200 mg, a protease inhibitor used as part of antiretroviral therapy for HIV. As a drug-specific HCPCS Level II code, S0140 is used in billing for pharmacy dispensing or outpatient administration of this antiretroviral formulation. Nationally, precise drug-level coding matters for inventory management, payer coverage determinations, formulary adjudication, and claims processing for HIV care.
Key payers covered in this overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an outline of the code’s clinical role and billing context, common modifiers applicable to HCPCS Level II drug claims (listed elsewhere), and notes on where the code is typically used in the care pathway (pharmacy and outpatient settings). The publication also points to typical benchmarking and policy considerations relevant to drug-specific HCPCS codes, including formulary alignment and coverage policies by major payers.
Data not available in the input includes associated taxonomies, specific ICD-10 diagnoses, and related codes; those items are noted as unavailable and are not fabricated.
Billing Code Overview
HCPCS Level II code S0140 represents Saquinavir, 200 mg, an antiretroviral medication formulation used in the treatment of HIV infection. The code denotes the drug product and dose supplied for pharmacy or medication administration billing.
Service Type: Pharmaceutical drug supply / antiretroviral therapy
Typical Site of Service: Pharmacy dispensing or outpatient clinic administration
Data not available in the input for associated taxonomies, ICD-10 diagnoses, and related service lines.
Clinical & Coding Specifications
Clinical Context
A patient with chronic HIV infection requiring antiretroviral therapy presents to an outpatient pharmacy or an infectious disease clinic for medication dispensing and adherence counseling. The clinician reviews prior regimen history, resistance testing, drug–drug interactions, and renal/hepatic function before prescribing. A prescription for S0140 (Saquinavir, 200 mg) is processed for dispensation; the pharmacy documents lot numbers, quantity, and billing details for the payor. Typical workflow includes verification by the pharmacist, patient education on administration with ritonavir boosting if indicated, scheduling follow-up viral load and CD4 testing, and billing the medication through medical or pharmacy benefits depending on the payer and site of service.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | Default/No modifier | Use when no special circumstances apply to the billed drug service |
22 | Increased procedural services | Rarely used for drug dispensing; use only if substantially greater resources were required for medication preparation or counseling documented separately |