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    v1.0.28
    OpenPayerBilling CodesMiscellaneous Medical ServicesHCPCS hcpcs-m0239-intravenous-bamlanivimab-infusion-with-monitoring
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    HCPCS Level II M0239: Intravenous Bamlanivimab Infusion with Monitoring

    HCPCS Level II code M0239 describes an intravenous infusion of bamlanivimab-xxxx and includes the infusion procedure plus post-administration monitoring; this service is an IV monoclonal antibody infusion typically performed in outpatient infusion centers or clinic-based infusion suites and billed as a combined infusion and observation service.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A 68-year-old patient with multiple comorbidities (type 2 diabetes, chronic kidney disease stage 3, and hypertension) presents to an outpatient infusion center within the manufacturer- and public-health-specified timeframe after testing positive for SARS-CoV-2 and experiencing mild-to-moderate COVID-19 symptoms. The ordering clinician documents eligibility for monoclonal antibody therapy and obtains informed consent. On arrival, nursing performs baseline vital signs, reviews allergies, and establishes IV access. The provider administers M0239 — intravenous infusion of bamlanivimab — with continuous monitoring during infusion and for a minimum post-administration observation period to watch for infusion reactions or anaphylaxis. Emergency medications and equipment are available. After monitoring, discharge instructions and return precautions are provided, and documentation includes indication, dose, lot number, infusion start/stop times, patient tolerance, and post-infusion status for billing and quality reporting.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    96365Intravenous infusion, for therapy, prophylaxis, or diagnosis; initial, up to 1 hourCommonly used for reporting initial IV infusion services when a specific HCPCS drug code is not used; documents infusion time and monitoring performed alongside drug administration workflows.
    96366Intravenous infusion, each additional hour (List separately in addition to code for primary service)Used when infusion extends beyond the initial hour and additional infusion time must be reported for clinical time tracking and billing where applicable.
    96372Therapeutic, prophylactic, or diagnostic injection; subcutaneous or intramuscularUsed for related injections such as ancillary vaccines or medications administered before or after infusion if applicable.
    36415Collection of venous blood by venipuncturePerformed for baseline labs (e.g., BMP) prior to or during the infusion episode when clinically indicated.
    99024Postoperative follow-up visit, normally included in the surgical package (example of global period-related codes)Occasionally used for related follow-up documentation workflows; inclusion depends on payer policy and is not ordinarily billed with monoclonal antibody infusion.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    56Modifier ‑56 indicates the reporting provider furnished only the preoperative management for a surgical procedure and did not perform the intraoperative or postoperative care. It is used in…- Use Modifier -56 when a provider performs only the preoperative management in a split‑care situation (one physician manages preop care while a different physician performs the intraoperative…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207Q00000XFamily Medicine PhysicianFamily Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
    208000000XPediatrics PhysicianA pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
    363LF0000XFamily Nurse PractitionerPhysician Assistants & Advanced Practice Nursing Providers · Nurse Practitioner
    282N00000XGeneral Acute Care HospitalAn acute general hospital is an institution whose primary function is to provide inpatient diagnostic and therapeutic services for a variety of medica…
    246XC2901XCardiovascular Invasive Specialist/TechnologistA cardiovascular invasive specialist/technologist monitors patients’ heart rates and helps physicians in diagnosing and treating heart problems. They …
    283XC2000XChildren's Rehabilitation HospitalHospitals · Rehabilitation Hospital
    314000000XSkilled Nursing Facility(1) A skilled nursing facility is a facility or distinct part of an institution whose primary function is to provide medical, continuous nursing, and …
    207RP1001XPulmonary Disease PhysicianAn internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational an…

    Related Codes

    HCPCS-M0075-CELLULAR-THERAPY-PROCESSING-PROVISION

    HCPCS Level II M0075: Cellular Therapy

    HCPCS-M0076-PROLOTHERAPY-INJECTION-THERAPY

    HCPCS Level II M0076: Prolotherapy

    HCPCS-M0100-INTRAGASTRIC-HYPOTHERMIA-GASTRIC-FREEZING

    HCPCS Level II M0100: Intragastric Hypothermia (Gastric Freezing)

    HCPCS-M0201-IN-HOME-VACCINE-ADMINISTRATION

    HCPCS Level II M0201: In-Home Vaccine Administration

    HCPCS-M0220-TIXAGEVIMAB-CILGAVIMAB-PRE-EXPOSURE-PROPHYLAXIS

    HCPCS Level II M0220: Tixagevimab and Cilgavimab Pre-Exposure Prophylaxis

    HCPCS-M0221-TIXAGEVIMAB-CILGAVIMAB-PRE-EXPOSURE-PROPHYLAXIS-HOME-ADMINISTRATION

    HCPCS M0221: Tixagevimab and Cilgavimab Pre-Exposure Prophylaxis

    HCPCS-M0222-BEBTELOVIMAB-INTRAVENOUS-INJECTION-MONITORING

    HCPCS Level II M0222: Bebtelovimab Intravenous Injection with Monitoring

    HCPCS-M0223-BEBTELOVIMAB-INTRAVENOUS-INJECTION-HOME-MONITORING

    HCPCS M0223: Intravenous Bebtelovimab with Home Monitoring

    HCPCS-M0224-PEMIVIBART-PRE-EXPOSURE-PROPHYLAXIS-INFUSION

    HCPCS M0224: Pemivibart Intravenous Infusion for Pre-Exposure Prophylaxis

    HCPCS-M0233-TOCILIZUMAB-INFUSION-COVID19-HOSPITALIZED-ADULTS

    HCPCS Level II M0233: Tocilizumab-aazg IV Infusion, First Dose

    Showing 1–10 of 27

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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