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    v1.0.28
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j1040-methylprednisolone-acetate-80mg-injection
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    HCPCS Level II J1040: Methylprednisolone Acetate Injection, 80 mg

    HCPCS Level II code J1040 represents an injection of methylprednisolone acetate, 80 mg, typically billed for an intramuscular or intra-articular corticosteroid administration intended to reduce inflammation; service type: medication administration (injectable corticosteroid), typical site of service: outpatient clinic, physician office, or ambulatory care setting.

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    Table of contents

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    • Billing CodesCPT, HCPCS, DRG & more
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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult with focal musculoskeletal pain from osteoarthritis, bursitis, tendinopathy, or an acute inflammatory flare who presents to an orthopedic clinic, sports medicine practice, pain management clinic, or an ambulatory surgery center. After history, focused physical exam, and review of prior imaging (plain radiographs, ultrasound, or MRI if available), the clinician discusses risks and benefits of a corticosteroid injection. Informed consent is obtained. The patient is positioned at the procedure table; the intended anatomic site (for example, a glenohumeral joint, subacromial space, knee joint, trochanteric bursa, or epidural space when appropriate) is prepped with antiseptic. Local anesthetic may be administered for skin and soft tissue anesthesia. Using landmark or image guidance (ultrasound or fluoroscopy), the clinician injects J1040 (methylprednisolone acetate, 80 mg) into the targeted site, often combined with local anesthetic per protocol. The patient is observed briefly for immediate adverse reaction and given post‑procedure instructions (activity modification, watch for infection or systemic steroid effects). Documentation includes indication, site, laterality, amount and specific agent J1040, technique (image guidance if used), any concurrent medications administered, consent, and post‑procedure status.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    20610Arthrocentesis, aspiration and/or injection; major joint or bursa (e.g., shoulder, hip, knee)Common CPT code for intra‑articular injection when J1040 is administered into a major joint
    20550Injection(s); single tendon sheath, or ligament, aponeurosis (e.g., trigger point)Used when steroid is injected into tendon sheath or small periarticular space
    76942Ultrasonic guidance for needle placement (eg, biopsy, aspiration, injection), imaging supervision and interpretationCoded when ultrasound guidance is used to place the needle for J1040 administration
    77003Fluoroscopic guidance for needle placement (eg, spine, discogram, myelogram)Used when fluoroscopic guidance is required for precise deposition of J1040, especially spine procedures
    99070Supplies and materials (except spectacles), provided by physician over and above those usually included with the office visit or other servicesUsed to report additional disposable supplies associated with the injection when payor requires separate reporting

    Related Modifiers

    6 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207X00000XOrthopaedic Surgery PhysicianAn orthopaedic surgeon is trained in the preservation, investigation and restoration of the form and function of the extremities, spine and associated…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    2084P0800XPsychiatry PhysicianA Psychiatrist specializes in the prevention, diagnosis, and treatment of mental disorders, emotional disorders, psychotic disorders, mood disorders, …
    208D00000XGeneral Practice PhysicianA physician who specializes in the general practice of diagnosing, treating, and managing patients with a variety of illnesses and conditions.
    363A00000XPhysician AssistantA physician assistant is a person who has successfully completed an accredited education program for physician assistant, is licensed by the state and…
    251300000XLocal Education Agency (LEA)The term local education agency means a public board of education or other public authority legally constituted within a State to either provide admin…
    246RP1900XPhlebotomy TechnicianTechnologists, Technicians & Other Technical Service Providers · Technician, Pathology
    133VN1101XGerontological Nutrition Registered DietitianAn individual who is a Specialist in Gerontological Nutrition and provides nutrition care to promote quality of life and optimal health for older adul…

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    G56.01Carpal tunnel syndrome, right upper limb
    M16.11Unilateral primary osteoarthritis, right hip
    M17.0Bilateral primary osteoarthritis of knee
    M17.11Unilateral primary osteoarthritis, right knee
    M17.12Unilateral primary osteoarthritis, left knee
    M19.071Primary osteoarthritis, right ankle and foot
    M19.072Primary osteoarthritis, left ankle and foot
    M23.211Derangement of anterior horn of medial meniscus due to old tear or injury, right knee
    M25.561Pain in right knee
    M25.562Pain in left knee

    Showing 1–10 of 27

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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