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    v1.0.30
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j1885-ketorolac-injection-15mg
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    HCPCS J1885: Injection of Ketorolac Tromethamine, per 15 mg

    HCPCS Level II code J1885 describes an injection of ketorolac tromethamine, per 15 mg used for short-term management of moderate to severe pain; the service is a parenteral non-opioid analgesic administration typically provided in hospital outpatient, emergency department, or ambulatory surgical settings where injectable NSAID therapy is indicated.

    For related coverage guidance, see recent payer policy updates: Hematology - Adzynma, Tumor Treating Fields for Pancreatic Cancer, Axicabtagene ciloleucel (Yescarta®) coverage.

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    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old patient presents to an urgent care clinic with acute moderate-to-severe musculoskeletal pain after a fall during weekend recreational activity. The patient reports pain localized to the right shoulder with limited range of motion and tenderness on palpation. After triage and brief evaluation by the clinician, nonsteroidal anti-inflammatory therapy is indicated for short-term pain control. The clinician determines that an intramuscular injection is appropriate because the patient requires rapid analgesia, oral intake is limited, or prior oral NSAIDs were ineffective or contraindicated.

    The clinical workflow: patient registration and allergy/medication reconciliation; focused history and physical exam documenting location, severity, onset, and functional impact of pain; assessment of contraindications to ketorolac (active bleeding, renal impairment, NSAID allergy, recent anticoagulant use, pregnancy); informed consent for injection; preparation of J1885 (ketorolac tromethamine) dose per 15 mg unit; administration via intramuscular or intravenous route as clinically indicated; monitoring for immediate adverse effects (bleeding, hypotension, allergic reaction); documentation of drug name, dose, route, lot number, site, patient response, and any counseling. Typical site of service: outpatient clinics, urgent care centers, emergency departments, and ambulatory surgical centers for short-term analgesia. Service type: pharmaceutical injectable non-chemotherapeutic, short-term analgesic (single-dose or short course injectable NSAID).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    96372Therapeutic, prophylactic, or diagnostic injection (specify substance or drug); subcutaneous or intramuscularCommonly used to report the administration of an intramuscular dose of J1885 when billing for the injection administration separately
    96365Intravenous infusion, for therapy, prophylaxis, or diagnosis; initial, up to 1 hourUsed if J1885 is administered intravenously as an initial infusion component in an observation or ED setting
    99202Office or other outpatient visit for the evaluation and management of a new patient, straightforward medical decision makingExample E/M codes that may be billed on the same day as J1885 when clinical evaluation warrants it and documentation supports 25 modifier
    99213Office or other outpatient visit for the evaluation and management of an established patient, low to moderate complexityCommon E/M level for follow-up or same-day established patient visits accompanying injection administration
    99070Supplies and materials (except spectacles), provided by the physician or other qualified health care professionalUsed to report additional supply costs related to injection administration (syringes, gloves) when payers allow separate billing

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    207R00000X
    363A00000X
    1223D0004X
    207RR0500X
    3336C0002X
    156FC0801X
    2086X0206X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    G89.3Neoplasm related pain (acute) (chronic)
    J02.9Acute pharyngitis, unspecified
    J06.9Acute upper respiratory infection, unspecified
    K21.9Gastro-esophageal reflux disease without esophagitis
    M17.11Unilateral primary osteoarthritis, right knee
    M17.12Unilateral primary osteoarthritis, left knee
    M25.561Pain in right knee
    M25.562Pain in left knee
    M51.26Other intervertebral disc displacement, lumbar region
    M54.12Radiculopathy, cervical region

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Hematology - AdzynmaCigna2026-10-15
    Tumor Treating Fields for Pancreatic Cancerselect_health2026-10-01
    Axicabtagene ciloleucel (Yescarta®) coverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Kentucky Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Kansas Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Idaho Only)UnitedHealthcare2026-10-01
    Brexucabtagene autoleucel (Tecartus) CoverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Pennsylvania Only)UnitedHealthcare2026-10-01
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Factor VIII ProductsCigna2026-09-15

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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