ICD-10-CM Code For Delirium Due To Known Physiological Condition: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group F05 includes acute delirium diagnoses attributable to an identifiable physiological cause, such as systemic infection, metabolic disturbance, or substance-induced states that impair attention and cognition. These ICD-10-CM diagnosis codes are used to document clinical scenarios where rapid cognitive change is linked to another medical condition, capturing severity, associated complications, and temporal relationship to the underlying cause. Accurate coding within the ICD-10-CM F05 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM F05: Delirium Due To Known Physiological Condition Overview

The ICD-10-CM F05 group represents acute and transient disturbances in attention and awareness caused by an underlying physiological condition. These diagnoses target neurocognitive and systemic conditions that acutely impair brain function, such as infections, metabolic derangements, or drug effects. Accurate coding matters for documenting clinical complexity and impacts reimbursement through correct claim classification.

When to Use

Use a code from this group when documentation indicates an acute confusional state or delirium explicitly linked to an identified physiological cause. Select the code that reflects the documented severity, associated features, and any specified underlying condition when available.

ICD-10-CM Codes

1 rows

ICD-10-CM Code	Description
F05	Delirium due to known physiological condition

DRG Codes

1 rows

DRG Code	Description
880	Acute Adjustment Reaction and Psychosocial Dysfunction

Typical Clinical Scenarios

An elderly patient is brought to the emergency department by family after acute onset of confusion, fluctuating attention, disorganized thinking, and an altered sleep–wake cycle following a urinary tract infection with fever and dehydration; the acute change from baseline and identification of an underlying medical trigger lead to assigning a delirium diagnosis due to a known physiological condition. Typical codes: F05.
A hospitalized middle-aged patient in the intensive care unit develops abrupt agitation, inattention, and perceptual disturbances after initiation of high-dose opioids and benzodiazepines for severe pain and sedation; because the cognitive disturbance is new, temporally related to identifiable medication effects, and not better explained by a primary psychiatric disorder, a diagnosis from this group is recorded. Typical codes: F05.
An older adult with advanced hepatic disease is admitted for management of liver failure and during the hospital stay exhibits acute fluctuating confusion, disorientation, and inappropriate behavior attributable to metabolic encephalopathy from the medical condition; the clinician assigns a delirium diagnosis linked to the known physiological cause as a comorbidity complicating care. Typical codes: F05.

Related Codes

F01-VASCULAR-DEMENTIA

ICD-10-CM Code For Vascular Dementia: Group Overview

F02-DEMENTIA-IN-OTHER-DISEASES

ICD-10-CM Code For Dementia In Other Diseases Classified Elsewhere: Group Overview

F03-UNSPECIFIED-DEMENTIA

ICD-10-CM Code For Unspecified Dementia: Group Overview

F04-AMNESTIC-DISORDER-DUE-TO-KNOWN-PHYSIOLOGICAL-CONDITION

ICD-10-CM Code For Amnestic Disorder Due To Known Physiological Condition: Group Overview

F06-OTHER-MENTAL-DISORDERS-SECONDARY

ICD-10-CM Code For Other Mental Disorders Due To Known Physiological Condition: Group Overview

F07-PERSONALITY-AND-BEHAVIORAL-DISORDERS

ICD-10-CM Code For Personality And Behavioral Disorders Due To Known Physiological Condition: Group Overview

F09-UNSPECIFIED-MENTAL-DISORDER

ICD-10-CM Code For Unspecified Mental Disorder Due To Known Physiological Condition: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

1 rows

ICD-10-CM Code	Description
F05	Delirium due to known physiological condition

DRG Codes

1 rows

DRG Code	Description
880	Acute Adjustment Reaction and Psychosocial Dysfunction

Typical Clinical Scenarios

An elderly patient is brought to the emergency department by family after acute onset of confusion, fluctuating attention, disorganized thinking, and an altered sleep–wake cycle following a urinary tract infection with fever and dehydration; the acute change from baseline and identification of an underlying medical trigger lead to assigning a delirium diagnosis due to a known physiological condition. Typical codes: F05.
A hospitalized middle-aged patient in the intensive care unit develops abrupt agitation, inattention, and perceptual disturbances after initiation of high-dose opioids and benzodiazepines for severe pain and sedation; because the cognitive disturbance is new, temporally related to identifiable medication effects, and not better explained by a primary psychiatric disorder, a diagnosis from this group is recorded. Typical codes: F05.
An older adult with advanced hepatic disease is admitted for management of liver failure and during the hospital stay exhibits acute fluctuating confusion, disorientation, and inappropriate behavior attributable to metabolic encephalopathy from the medical condition; the clinician assigns a delirium diagnosis linked to the known physiological cause as a comorbidity complicating care. Typical codes: F05.

Related Codes

F01-VASCULAR-DEMENTIA

ICD-10-CM Code For Vascular Dementia: Group Overview

F02-DEMENTIA-IN-OTHER-DISEASES

ICD-10-CM Code For Dementia In Other Diseases Classified Elsewhere: Group Overview

F03-UNSPECIFIED-DEMENTIA

ICD-10-CM Code For Unspecified Dementia: Group Overview

F04-AMNESTIC-DISORDER-DUE-TO-KNOWN-PHYSIOLOGICAL-CONDITION

ICD-10-CM Code For Amnestic Disorder Due To Known Physiological Condition: Group Overview

F06-OTHER-MENTAL-DISORDERS-SECONDARY

ICD-10-CM Code For Other Mental Disorders Due To Known Physiological Condition: Group Overview

F07-PERSONALITY-AND-BEHAVIORAL-DISORDERS

ICD-10-CM Code For Personality And Behavioral Disorders Due To Known Physiological Condition: Group Overview

F09-UNSPECIFIED-MENTAL-DISORDER

ICD-10-CM Code For Unspecified Mental Disorder Due To Known Physiological Condition: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Delirium Due To Known Physiological Condition: Group Overview

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ICD-10-CM F05: Delirium Due To Known Physiological Condition Overview

ICD-10-CM Code For Delirium Due To Known Physiological Condition: Group Overview

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ICD-10-CM F05: Delirium Due To Known Physiological Condition Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What does ICD-10-CM code group `F05` represent?

When should a clinician document a diagnosis under `F05`?

How does coding `F05` affect claims and reimbursement?

What types of underlying conditions are associated with `F05` diagnoses?

Which DRG is related to the `F05` diagnosis group?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What does ICD-10-CM code group `F05` represent?

When should a clinician document a diagnosis under `F05`?

How does coding `F05` affect claims and reimbursement?

What types of underlying conditions are associated with `F05` diagnoses?

Which DRG is related to the `F05` diagnosis group?

References