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    OpenPayerBilling CodesDiabetes mellitusICD-10-CM e08-diabetes-mellitus-due-to-underlying-condition
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    ICD-10-CM Code For Diabetes Mellitus Due To Underlying Condition: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E08 includes diabetes mellitus attributable to an underlying condition, capturing instances where hyperglycemia results from another disease process or condition such as pancreatic disease, endocrine disorders, or medication effects. These ICD-10-CM diagnosis codes are used to document clinical scenarios that identify the causal relationship, capture disease severity, and note organ system involvement or complications related to secondary diabetes. Accurate coding within the ICD-10-CM E08 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM E08: Diabetes Mellitus Due To Underlying Condition Overview

    The ICD-10-CM E08 diagnosis group represents diabetes mellitus caused by an identifiable underlying condition, such as endocrine disorders, diseases of the pancreas, or medication-induced hyperglycemia. These codes target the metabolic and endocrine systems and specify when hyperglycemia is secondary to another disorder rather than primary type 1 or type 2 diabetes. Accurate coding matters for correct clinical documentation and for supporting appropriate reimbursement by reflecting the causal relationship between the underlying condition and diabetes.

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    When to Use

    Use a code from this group when documentation indicates that hyperglycemia or diabetes is secondary to a specific underlying condition, such as pancreatic disease, endocrine disorders, infections, or medication effects. Select the code that identifies the underlying condition and include additional codes for any documented diabetes complications or manifestations.

    ICD-10-CM Codes

    86 rows

    ICD-10-CM CodeDescription
    E08.00Diabetes mellitus due to underlying condition with hyperosmolarity without nonketotic hyperglycemic-hyperosmolar coma (NKHHC)
    E08.01Diabetes mellitus due to underlying condition with hyperosmolarity with coma
    E08.10Diabetes mellitus due to underlying condition with ketoacidosis without coma
    E08.11Diabetes mellitus due to underlying condition with ketoacidosis with coma
    E08.21Diabetes mellitus due to underlying condition with diabetic nephropathy
    E08.22Diabetes mellitus due to underlying condition with diabetic chronic kidney disease
    E08.29Diabetes mellitus due to underlying condition with other diabetic kidney complication
    E08.311Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy with macular edema
    E08.319Diabetes mellitus due to underlying condition with unspecified diabetic retinopathy without macular edema
    E08.3211Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, right eye
    E08.3212Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, left eye
    E08.3213Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, bilateral
    E08.3219Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy with macular edema, unspecified eye
    E08.3291Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, right eye
    E08.3292Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, left eye
    E08.3293Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, bilateral
    E08.3299Diabetes mellitus due to underlying condition with mild nonproliferative diabetic retinopathy without macular edema, unspecified eye
    E08.3311Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, right eye
    E08.3312Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, left eye
    E08.3313Diabetes mellitus due to underlying condition with moderate nonproliferative diabetic retinopathy with macular edema, bilateral

    Showing 1–20 of 86

    DRG Codes

    16 rows

    DRG CodeDescription
    008Simultaneous Pancreas and Kidney Transplant
    010Pancreas Transplant
    019Simultaneous Pancreas and Kidney Transplant with Hemodialysis
    073Cranial and Peripheral Nerve Disorders with MCC
    074Cranial and Peripheral Nerve Disorders without MCC
    124Other Disorders of the Eye with MCC or Thrombolytic Agent
    125Other Disorders of the Eye without MCC
    299Peripheral Vascular Disorders with MCC
    300Peripheral Vascular Disorders with CC
    301Peripheral Vascular Disorders without CC/MCC
    637Diabetes with MCC
    638Diabetes with CC
    639Diabetes without CC/MCC
    698Other Kidney and Urinary Tract Diagnoses with MCC
    699Other Kidney and Urinary Tract Diagnoses with CC
    700Other Kidney and Urinary Tract Diagnoses without CC/MCC

    Typical Clinical Scenarios

    • A middle-aged patient with long-standing chronic pancreatitis presents to the outpatient endocrinology clinic for worsening hyperglycemia and increased polyuria despite oral agents. Laboratory testing shows elevated fasting glucose and hemoglobin A1c consistent with diabetes caused by pancreatic disease; therapy is being adjusted and diabetes due to the underlying pancreatic condition is documented. Typical codes: E08.9, E08.65
    • An older adult is brought to the emergency department with altered mental status and dehydration after a urinary tract infection; point-of-care testing reveals marked hyperglycemia and a hyperosmolar state attributed to corticosteroid therapy for a recent COPD exacerbation. Because the hyperglycemia is secondary to a known medication and has acute metabolic complications requiring inpatient management, a code from this group for diabetes due to an underlying condition with hyperosmolarity is assigned. Typical codes: E08.00, E08.01
    • A patient with chronic kidney disease secondary to systemic lupus erythematosus is hospitalized for progressive diabetic foot ulcer with surrounding cellulitis; the diabetes is determined to be a consequence of the patient’s underlying condition and is contributing to poor wound healing and peripheral vascular complications. A code reflecting diabetes due to an underlying condition with skin ulcer or infection is used to capture the complication and guide care documentation. Typical codes: E08.621, E08.621

    Related Codes

    E09-DRUG-OR-CHEMICAL-INDUCED-DIABETES-MELLITUS

    ICD-10-CM Code For Drug Or Chemical Induced Diabetes Mellitus: Group Overview

    E10-TYPE-1-DIABETES-MELLITUS

    ICD-10-CM Code For Type 1 Diabetes Mellitus: Group Overview

    E11-TYPE-2-DIABETES-MELLITUS

    ICD-10-CM Code For Type 2 Diabetes Mellitus: Group Overview

    E13-OTHER-SPECIFIED-DIABETES-MELLITUS

    ICD-10-CM Code For Other Specified Diabetes Mellitus: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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