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    OpenPayerBilling CodesDisorders of thyroid glandICD-10-CM e05-thyrotoxicosis-hyperthyroidism
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    ICD-10-CM Code For Thyrotoxicosis Hyperthyroidism: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E05 includes diagnoses of thyrotoxicosis and hyperthyroidism, covering conditions caused by excess thyroid hormone production or release such as Graves disease, toxic multinodular goiter, and thyroiditis-related thyrotoxicosis. These ICD-10-CM diagnosis codes are used to document clinical scenarios including new-onset hyperthyroid states, exacerbations, and organ-specific complications like atrial arrhythmias or thyrotoxic crisis, capturing disease severity and clinical complexity relevant to this group. Accurate coding within the ICD-10-CM E05 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM E05: Thyrotoxicosis [hyperthyroidism] Overview

    This group includes diagnoses of thyrotoxicosis or hyperthyroidism, conditions characterized by excess circulating thyroid hormones affecting multiple organ systems. It targets the endocrine system, with clinical manifestations ranging from metabolic acceleration to cardiovascular and neurologic effects. Accurate coding is important for complete clinical documentation and can affect reimbursement and claim processing.

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    When to Use

    Use a code from this group when a clinician documents hyperthyroid states or thyrotoxic symptoms attributable to an identified thyroid disorder. Codes are also used for coding complications or acute severe presentations like thyrotoxic crisis when documented by the provider.

    ICD-10-CM Codes

    14 rows

    ICD-10-CM CodeDescription
    E05.00Thyrotoxicosis with diffuse goiter without thyrotoxic crisis or storm
    E05.01Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm
    E05.10Thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis or storm
    E05.11Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis or storm
    E05.20Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis or storm
    E05.21Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis or storm
    E05.30Thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis or storm
    E05.31Thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis or storm
    E05.40Thyrotoxicosis factitia without thyrotoxic crisis or storm
    E05.41Thyrotoxicosis factitia with thyrotoxic crisis or storm
    E05.80Other thyrotoxicosis without thyrotoxic crisis or storm
    E05.81Other thyrotoxicosis with thyrotoxic crisis or storm
    E05.90Thyrotoxicosis, unspecified without thyrotoxic crisis or storm
    E05.91Thyrotoxicosis, unspecified with thyrotoxic crisis or storm

    DRG Codes

    6 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    643Endocrine Disorders with MCC
    644Endocrine Disorders with CC
    645Endocrine Disorders without CC/MCC

    Typical Clinical Scenarios

    • An elderly patient presents to the emergency department with acute onset palpitations, atrial fibrillation with rapid ventricular response, heat intolerance, tremor, and weight loss over several weeks. The ED documents laboratory-confirmed thyrotoxicosis and attributes the new atrial fibrillation and hemodynamic symptoms to the hyperthyroid state, prompting urgent management. Typical codes: E05.20, E05.21
    • A young adult with known Graves disease attends endocrinology follow-up for chronic management; they report persistent symptoms of nervousness, mild tachycardia, and difficulty controlling weight despite antithyroid medication, and labs show continued suppressed TSH. The visit documents ongoing thyrotoxicosis due to autoimmune hyperfunction and adjustments to long-term therapy are considered. Typical codes: E05.30, E05.31
    • A postpartum woman presents to her primary care clinician several weeks after delivery with fatigue, irritability, palpitations, and a tender, mildly enlarged thyroid; thyroid function tests confirm transient thyrotoxicosis likely from subacute or postpartum thyroiditis with symptomatic management recommended. Typical codes: E05.40, E05.41

    Related Codes

    E00-CONGENITAL-IODINE-DEFICIENCY-SYNDROME

    ICD-10-CM Code For Congenital Iodine-Deficiency Syndrome: Group Overview

    E01-IODINE-DEFICIENCY-THYROID-DISORDERS

    ICD-10-CM Code For Iodine-Deficiency Related Thyroid Disorders And Allied Conditions: Group Overview

    E02-SUBCLINICAL-IODINE-DEFICIENCY-HYPOTHYROIDISM

    ICD-10-CM Code For Subclinical Iodine-Deficiency Hypothyroidism: Group Overview

    E03-OTHER-HYPOTHYROIDISM

    ICD-10-CM Code For Other Hypothyroidism: Group Overview

    E04-OTHER-NONTOXIC-GOITER

    ICD-10-CM Code For Other Nontoxic Goiter: Group Overview

    E06-THYROIDITIS

    ICD-10-CM Code For Thyroiditis: Group Overview

    E07-OTHER-DISORDERS-OF-THYROID

    ICD-10-CM Code For Other Disorders Of Thyroid: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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