ICD-10-PCS Code For Pleura: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group DB25 includes procedures performed to stereotactically deliver therapeutic radiation to the pleura in the respiratory system. These ICD-10-PCS codes are used for inpatient documentation when focused radiation treatment is provided to pleural lesions or disease processes requiring stereotactic accuracy. Accurate coding within the ICD-10-PCS DB25 group is essential for proper inpatient reimbursement, as it captures the specific procedure performed and supports clinical documentation accuracy.

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Pleura Stereotactic Radiosurgery Procedure Overview

Procedures in this group involve stereotactic radiosurgery targeting the pleura within the respiratory system. These interventions deliver precisely focused radiation to pleural tissues to treat localized lesions while sparing surrounding structures. Accurate ICD-10-PCS coding of these procedures ensures inpatient records reflect the specific operation and anatomical target, which affects case mix group assignment and reimbursement.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
D	Section	Radiation Therapy
B	Body System	Respiratory System
2	Operation	Stereotactic Radiosurgery
5	Body Part	Pleura

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ICD-10-PCS Code For Pleura: Procedure Code Group Overview

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Pleura Stereotactic Radiosurgery Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
D	Section	Radiation Therapy
B	Body System	Respiratory System
2	Operation	Stereotactic Radiosurgery
5	Body Part	Pleura

When to Use

Use a code from this group when stereotactic radiosurgery is performed on the pleura for treatment of localized pleural tumors, metastases, or other focal disease requiring precise radiation delivery. Codes should be selected when inpatient documentation confirms the use of stereotactic guidance and targeting to the pleural anatomical site.

ICD-10-PCS Codes

3 rows

ICD-10-PCS Code	Description
DB25DZZ	Stereotactic Other Photon Radiosurgery of Pleura
DB25HZZ	Stereotactic Particulate Radiosurgery of Pleura
DB25JZZ	Stereotactic Gamma Beam Radiosurgery of Pleura

DRG Codes

12 rows

DRG Code	Description
040	Peripheral, Cranial Nerve and Other Nervous System Procedures with MCC
041	Peripheral, Cranial Nerve and Other Nervous System Procedures with CC or Peripheral Neurostimulator
042	Peripheral, Cranial Nerve and Other Nervous System Procedures without CC/MCC
628	Other Endocrine, Nutritional and Metabolic O.R. Procedures with MCC
629	Other Endocrine, Nutritional and Metabolic O.R. Procedures with CC
630	Other Endocrine, Nutritional and Metabolic O.R. Procedures without CC/MCC
823	Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
824	Lymphoma and Non-Acute Leukemia with Other Procedures with CC
825	Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC
829	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Other Procedures with CC/MCC

Showing 1–10 of 12

Typical Clinical Scenarios

An elderly patient with a solitary pleural metastasis from non–small cell lung cancer presents for a planned inpatient stereotactic radiation session to achieve high-dose focal control while minimizing exposure to adjacent lung tissue. Pre-procedural imaging and stereotactic targeting are used to deliver precise photon beams to the pleural lesion as part of a multimodality treatment plan. The focused photon approach is chosen to ablate the discrete pleural tumor while preserving pulmonary function. Typical codes: DB25DZZ
A middle-aged patient is admitted urgently for symptomatic control of a painful, isolated pleural recurrence after prior systemic therapy; stereotactic radiosurgery is performed to rapidly reduce tumor burden and relieve pleural pain. Stereotactic particulate radiotherapy is used to deposit therapeutic particulate radiation precisely into the targeted pleural region under image guidance during the inpatient stay. This approach is selected when localization and high conformality are required to limit dose to surrounding respiratory structures. Typical codes: DB25HZZ
A patient with a radioresistant pleural lesion previously treated with conventional external beam therapy undergoes a focused gamma beam stereotactic procedure during a short inpatient admission for re-treatment of the persistent pleural tumor. The gamma beam delivers concentrated dose to the recurrent pleural focus with stereotactic accuracy to attempt local control while respecting prior dose constraints. The case represents a re-treatment scenario where precision gamma radiosurgery is used due to prior therapy and the need for maximal sparing of surrounding lung. Typical codes: DB25JZZ

ICD-10-PCS Code For Trachea: Procedure Code Group Overview

DB21-BRONCHUS-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Bronchus: Procedure Code Group Overview

DB22-LUNG-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Lung: Procedure Code Group Overview

DB26-MEDIASTINUM-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Mediastinum: Procedure Code Group Overview

DB27-CHEST-WALL-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Chest Wall: Procedure Code Group Overview

DB28-DIAPHRAGM-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Diaphragm: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

3 rows

ICD-10-PCS Code	Description
DB25DZZ	Stereotactic Other Photon Radiosurgery of Pleura
DB25HZZ	Stereotactic Particulate Radiosurgery of Pleura
DB25JZZ	Stereotactic Gamma Beam Radiosurgery of Pleura

DRG Codes

12 rows

DRG Code	Description
040	Peripheral, Cranial Nerve and Other Nervous System Procedures with MCC
041	Peripheral, Cranial Nerve and Other Nervous System Procedures with CC or Peripheral Neurostimulator
042	Peripheral, Cranial Nerve and Other Nervous System Procedures without CC/MCC
628	Other Endocrine, Nutritional and Metabolic O.R. Procedures with MCC
629	Other Endocrine, Nutritional and Metabolic O.R. Procedures with CC
630	Other Endocrine, Nutritional and Metabolic O.R. Procedures without CC/MCC
823	Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
824	Lymphoma and Non-Acute Leukemia with Other Procedures with CC
825	Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC
829	Myeloproliferative Disorders or Poorly Differentiated Neoplasms with Other Procedures with CC/MCC

Showing 1–10 of 12

Typical Clinical Scenarios

An elderly patient with a solitary pleural metastasis from non–small cell lung cancer presents for a planned inpatient stereotactic radiation session to achieve high-dose focal control while minimizing exposure to adjacent lung tissue. Pre-procedural imaging and stereotactic targeting are used to deliver precise photon beams to the pleural lesion as part of a multimodality treatment plan. The focused photon approach is chosen to ablate the discrete pleural tumor while preserving pulmonary function. Typical codes: DB25DZZ
A middle-aged patient is admitted urgently for symptomatic control of a painful, isolated pleural recurrence after prior systemic therapy; stereotactic radiosurgery is performed to rapidly reduce tumor burden and relieve pleural pain. Stereotactic particulate radiotherapy is used to deposit therapeutic particulate radiation precisely into the targeted pleural region under image guidance during the inpatient stay. This approach is selected when localization and high conformality are required to limit dose to surrounding respiratory structures. Typical codes: DB25HZZ
A patient with a radioresistant pleural lesion previously treated with conventional external beam therapy undergoes a focused gamma beam stereotactic procedure during a short inpatient admission for re-treatment of the persistent pleural tumor. The gamma beam delivers concentrated dose to the recurrent pleural focus with stereotactic accuracy to attempt local control while respecting prior dose constraints. The case represents a re-treatment scenario where precision gamma radiosurgery is used due to prior therapy and the need for maximal sparing of surrounding lung. Typical codes: DB25JZZ

ICD-10-PCS Code For Trachea: Procedure Code Group Overview

DB21-BRONCHUS-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Bronchus: Procedure Code Group Overview

DB22-LUNG-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Lung: Procedure Code Group Overview

DB26-MEDIASTINUM-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Mediastinum: Procedure Code Group Overview

DB27-CHEST-WALL-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Chest Wall: Procedure Code Group Overview

DB28-DIAPHRAGM-STEREOTACTIC-RADIOSURGERY

ICD-10-PCS Code For Diaphragm: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

ICD-10-PCS Code For Pleura: Procedure Code Group Overview

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Pleura Stereotactic Radiosurgery Procedure Overview

Code Attributes

OpenPayer

ICD-10-PCS Code For Pleura: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pleura: Procedure Code Group Overview policy alerts

Pleura Stereotactic Radiosurgery Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Pleura: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pleura: Procedure Code Group Overview policy alerts

Pleura Stereotactic Radiosurgery Procedure Overview

Code Attributes

ICD-10-PCS Code For Pleura: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Pleura: Procedure Code Group Overview policy alerts

Pleura Stereotactic Radiosurgery Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code group covers stereotactic radiosurgery procedures targeting the pleura?

What are the specific ICD-10-PCS codes included in the DB25 group?

What are the section, body system, operation, and body part attributes for DB25 codes?

Why is accurate coding within the DB25 group important for inpatient records?

Which DRG categories are related to procedures in the DB25 code group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code group covers stereotactic radiosurgery procedures targeting the pleura?

What are the specific ICD-10-PCS codes included in the DB25 group?

What are the section, body system, operation, and body part attributes for DB25 codes?

Why is accurate coding within the DB25 group important for inpatient records?

Which DRG categories are related to procedures in the DB25 code group?

References