ICD-10-CM Code For Other Nutritional Anemias: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D53 includes other nutritional anemias such as folate deficiency anemia and anemias due to other specified nutritional deficiencies that cause impaired red blood cell production and morphological changes. These ICD-10-CM diagnosis codes are used to document clinical scenarios including deficiency-related anemia severity, related hematologic findings, and treatment requirements such as nutritional supplementation or monitoring. Accurate coding within the ICD-10-CM D53 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM D53: Other Nutritional Anemias Overview

The ICD-10-CM D53 group includes other nutritional anemias caused by deficiencies in nutrients such as folate and other specified vitamins. These diagnoses affect the hematologic system and result in reduced red blood cell production or abnormal cell morphology. Accurate coding matters because it supports appropriate clinical documentation and reimbursement for treatments related to nutritional deficiencies and anemia management.

When to Use

Use a code from this group when a clinical diagnosis attributes anemia to a specific nutritional deficiency such as folate or another vitamin deficiency confirmed by laboratory testing or clinical assessment. Select the most specific code that reflects the identified nutrient cause and any documented severity or related complications.

ICD-10-CM Codes

5 rows

ICD-10-CM Code	Description
D53.0	Protein deficiency anemia
D53.1	Other megaloblastic anemias, not elsewhere classified
D53.2	Scorbutic anemia
D53.8	Other specified nutritional anemias
D53.9	Nutritional anemia, unspecified

DRG Codes

2 rows

DRG Code	Description
811	Red Blood Cell Disorders with MCC
812	Red Blood Cell Disorders without MCC

Typical Clinical Scenarios

Elderly patient with progressive fatigue, pallor, and shortness of breath over months who is found on outpatient labs to have macrocytic anemia with low serum folate and normal B12; dietary history reveals poor oral intake and chronic alcohol use, and treatment initiation is coordinated with primary care. A nutritional deficiency is identified as the primary cause of the anemia, so a code from this group reflecting folate deficiency is assigned. Typical codes: D53.0
Pregnant woman in her second trimester presenting for routine prenatal care with mild anemia on screening hemoglobin and documented folate deficiency; she has no acute symptoms but requires monitoring and supplementation to prevent adverse fetal outcomes. Because the anemia is related to pregnancy-associated increased requirements and confirmed folate deficiency, a nutritional anemia code from this group is used. Typical codes: D53.1, D53.0
Patient with chronic inflammatory bowel disease and malabsorption who is hospitalized for a disease flare and found to have symptomatic anemia attributable to multiple nutritional deficiencies despite prior supplementation; this anemia is recorded as a comorbidity affecting inpatient care and management complexity. A code from this group representing nutritional anemia due to other specified deficiencies or unspecified nutritional anemia is assigned alongside the IBD diagnosis. Typical codes: D53.8, D53.9

Related Codes

D50-IRON-DEFICIENCY-ANEMIA

ICD-10-CM Code For Iron Deficiency Anemia: Group Overview

D51-VITAMIN-B12-DEFICIENCY-ANEMIA

ICD-10-CM Code For Vitamin B12 Deficiency Anemia: Group Overview

D52-FOLATE-DEFICIENCY-ANEMIA

ICD-10-CM Code For Folate Deficiency Anemia: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

5 rows

ICD-10-CM Code	Description
D53.0	Protein deficiency anemia
D53.1	Other megaloblastic anemias, not elsewhere classified
D53.2	Scorbutic anemia
D53.8	Other specified nutritional anemias
D53.9	Nutritional anemia, unspecified

DRG Codes

2 rows

DRG Code	Description
811	Red Blood Cell Disorders with MCC
812	Red Blood Cell Disorders without MCC

Typical Clinical Scenarios

Elderly patient with progressive fatigue, pallor, and shortness of breath over months who is found on outpatient labs to have macrocytic anemia with low serum folate and normal B12; dietary history reveals poor oral intake and chronic alcohol use, and treatment initiation is coordinated with primary care. A nutritional deficiency is identified as the primary cause of the anemia, so a code from this group reflecting folate deficiency is assigned. Typical codes: D53.0
Pregnant woman in her second trimester presenting for routine prenatal care with mild anemia on screening hemoglobin and documented folate deficiency; she has no acute symptoms but requires monitoring and supplementation to prevent adverse fetal outcomes. Because the anemia is related to pregnancy-associated increased requirements and confirmed folate deficiency, a nutritional anemia code from this group is used. Typical codes: D53.1, D53.0
Patient with chronic inflammatory bowel disease and malabsorption who is hospitalized for a disease flare and found to have symptomatic anemia attributable to multiple nutritional deficiencies despite prior supplementation; this anemia is recorded as a comorbidity affecting inpatient care and management complexity. A code from this group representing nutritional anemia due to other specified deficiencies or unspecified nutritional anemia is assigned alongside the IBD diagnosis. Typical codes: D53.8, D53.9

Related Codes

D50-IRON-DEFICIENCY-ANEMIA

ICD-10-CM Code For Iron Deficiency Anemia: Group Overview

D51-VITAMIN-B12-DEFICIENCY-ANEMIA

ICD-10-CM Code For Vitamin B12 Deficiency Anemia: Group Overview

D52-FOLATE-DEFICIENCY-ANEMIA

ICD-10-CM Code For Folate Deficiency Anemia: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Other Nutritional Anemias: Group Overview

Sign up for ICD-10-CM Code For Other Nutritional Anemias: Group Overview policy alerts

ICD-10-CM D53: Other Nutritional Anemias Overview

ICD-10-CM Code For Other Nutritional Anemias: Group Overview

Sign up for ICD-10-CM Code For Other Nutritional Anemias: Group Overview policy alerts

ICD-10-CM D53: Other Nutritional Anemias Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which diagnoses are included in the ICD-10-CM D53 group?

How does accurate coding within D53 affect reimbursement?

What clinical scenarios are documented using D53 codes?

Which DRGs are related to the D53 diagnosis group?

What documentation focus is important when assigning a `D53` code?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which diagnoses are included in the ICD-10-CM D53 group?

How does accurate coding within D53 affect reimbursement?

What clinical scenarios are documented using D53 codes?

Which DRGs are related to the D53 diagnosis group?

What documentation focus is important when assigning a `D53` code?

References