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    v1.0.28
    OpenPayerBilling CodesBenign neoplasms, except benign neuroendocrine tumorsICD-10-CM d25-leiomyoma-of-uterus
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    ICD-10-CM Code For Leiomyoma Of Uterus: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D25 includes benign uterine smooth muscle tumors (leiomyomas) classified by location and symptom presence, covering conditions such as intramural, submucosal, and multiple leiomyomas. These ICD-10-CM diagnosis codes are used to document clinical encounters involving symptomatic or asymptomatic uterine fibroids, capturing disease location, multiplicity, and related complications when applicable. Accurate coding within the ICD-10-CM D25 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM D25: Leiomyoma Of Uterus Overview

    The ICD-10-CM D25 code group represents benign smooth muscle tumors of the uterus, commonly known as uterine fibroids or leiomyomas. These diagnoses target the female reproductive system and encompass variants by location and symptomatology, such as submucosal, intramural, and subserosal leiomyomas. Accurate coding matters for appropriate claim processing and to reflect clinical complexity that affects treatment planning and resource use.

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    When to Use

    Use a code from this group when documenting a diagnosis of uterine leiomyoma or fibroid identified clinically, radiologically, or surgically, with the code choice reflecting tumor location and multiplicity. Select additional codes for associated symptoms or complications when they are clinically relevant and documented in the record.

    ICD-10-CM Codes

    4 rows

    ICD-10-CM CodeDescription
    D25.0Submucous leiomyoma of uterus
    D25.1Intramural leiomyoma of uterus
    D25.2Subserosal leiomyoma of uterus
    D25.9Leiomyoma of uterus, unspecified

    DRG Codes

    4 rows

    DRG CodeDescription
    742Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC
    743Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC
    760Menstrual and Other Female Reproductive System Disorders with CC/MCC
    761Menstrual and Other Female Reproductive System Disorders without CC/MCC

    Typical Clinical Scenarios

    • A 38-year-old woman with a history of heavy, prolonged menstrual bleeding reports progressive anemia and pelvic pressure. Pelvic exam and transvaginal ultrasound identify a single large mass arising from the uterine wall consistent with an intramural fibroid causing bulk symptoms and menorrhagia; she presents for medical management and possible surgical planning. Typical codes: D25.2, D25.9
    • A 29-year-old nulliparous patient presents to the fertility clinic with difficulty conceiving; imaging reveals multiple submucosal uterine fibroids distorting the endometrial cavity and likely contributing to implantation failure and recurrent miscarriage. A diagnosis from the group is assigned to document fibroid location and severity as part of the infertility workup and to guide hysteroscopic or surgical intervention planning. Typical codes: D25.0, D25.1
    • A 46-year-old perimenopausal woman arrives to the emergency department with acute urinary retention and severe lower abdominal pain; imaging shows a pedunculated subserosal fibroid undergoing torsion and causing acute mass effect. The acute presentation and fibroid-related complication prompt assignment of a code from the group to capture the benign neoplasm causing the emergency. Typical codes: D25.1, D25.9

    Related Codes

    D10-BENIGN-NEOPLASM-OF-MOUTH-AND-PHARYNX

    ICD-10-CM Code For Benign Neoplasm Of Mouth And Pharynx: Group Overview

    D11-BENIGN-NEOPLASM-MAJOR-SALIVARY-GLANDS

    ICD-10-CM Code For Benign Neoplasm Of Major Salivary Glands: Group Overview

    D12-BENIGN-NEOPLASM-COLON-RECTUM-ANUS

    ICD-10-CM Code For Benign Neoplasm Of Colon Rectum Anus And Anal Canal: Group Overview

    D13-BENIGN-NEOPLASM-OTHER-DIGESTIVE

    ICD-10-CM Code For Benign Neoplasm Of Other And Ill-Defined Parts Of Digestive System: Group Overview

    D14-BENIGN-MIDDLE-EAR-AND-RESPIRATORY-NEOPLASMS

    ICD-10-CM Code For Benign Neoplasm Of Middle Ear And Respiratory System: Group Overview

    D15-BENIGN-NEOPLASM-INTRATHORACIC-ORGANS

    ICD-10-CM Code For Benign Neoplasm Of Other And Unspecified Intrathoracic Organs: Group Overview

    D16-BENIGN-NEOPLASM-OF-BONE

    ICD-10-CM Code For Benign Neoplasm Of Bone And Articular Cartilage: Group Overview

    D17-BENIGN-LIPOMATOUS-NEOPLASM

    ICD-10-CM Code For Benign Lipomatous Neoplasm: Group Overview

    D18-HEMANGIOMA-AND-LYMPHANGIOMA

    ICD-10-CM Code For Hemangioma And Lymphangioma, Any Site: Group Overview

    D19-BENIGN-MESOTHELIAL-NEOPLASMS

    ICD-10-CM Code For Benign Neoplasm Of Mesothelial Tissue: Group Overview

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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