CPT code 88299 reports an unlisted cytogenetic procedure performed when no specific CPT code applies; the service represents miscellaneous cytogenetic testing such as karyotyping or chromosome analysis variants and is typically billed for clinical laboratory cytogenetics services provided in an outpatient laboratory, hospital laboratory, or clinical cytogenetics lab setting.

For related coverage guidance, see recent payer policy updates: RTM Testing of Homocysteine Metabolism-Related Conditions, Multimarker Serum Testing Related to Ovarian Cancer, Genomic Profiling for Selecting Targeted Cancer Therapies.