CPT code 88267 identifies a prenatal cytogenetic procedure: chromosome analysis (karyotype) on cells from amniotic fluid or chorionic villus, with counting of 15 cells and preparation of one banded karyotype. This testing is a key diagnostic tool in prenatal care to detect aneuploidies and large chromosomal rearrangements that can impact pregnancy management and counseling. Nationally, prenatal cytogenetic testing remains a relevant component of maternal-fetal services due to ongoing prenatal screening programs and referrals from obstetric providers.

Key payers considered in this overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The content summarizes clinical context, typical sites of service (hospital or specialized clinical laboratories), and what readers can expect from the full publication: benchmark billing and utilization context, coding and clinical scope, and policy or reimbursement considerations affecting access to prenatal cytogenetic services. Where payer-specific coverage patterns or edits exist, those are summarized in the detailed sections of the publication. Data not available in the input is noted where applicable.