CPT code 87535 denotes a molecular laboratory assay that uses an amplified probe technique to provide a definitive diagnosis of HIV‑1. As a confirmatory molecular diagnostic, this test is clinically important for accurate identification of HIV‑1 infection, guiding linkage to care and appropriate clinical management. Nationally, confirmatory HIV testing remains a priority for public health, laboratory reporting, and payer coverage policies.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context and use cases for CPT code 87535, typical sites of service, and the types of benchmarks and policy elements commonly relevant to molecular HIV diagnostics. The publication discusses reimbursement benchmarking, common billing considerations, and recent policy themes affecting laboratory molecular testing reimbursement and coverage. Where input data is not provided, the report notes that specific payer rates, associated taxonomies, and ICD‑10 pairings are not available in the input.