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CPT 87380: Hepatitis D (Delta) Antigen Immunoassay
CPT code 87380 represents an immunoassay performed to detect antigens of hepatitis D (delta agent). This laboratory diagnostic code is used when a clinical laboratory conducts antigen testing for hepatitis D, commonly via enzyme immunoassay (EIA) techniques. The code matters nationally because hepatitis D is a serious viral co-infection that alters clinical management and public health reporting for patients with hepatitis B virus infection.
Key payers discussed in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context for antigen testing, typical sites of service (clinical and hospital laboratories), and the role of antigen assays in confirming hepatitis D infection. The publication also outlines common billing modifiers associated with laboratory services and highlights what to expect in payer coverage patterns and coding practice trends.
This summary equips laboratory managers, billing professionals, and policy analysts with a focused reference on CPT code 87380, clarifying the test purpose, care setting, and the payers commonly engaged in coverage and reimbursement. Data not available in the input will be noted where applicable in supporting sections.
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Billing Code Overview
CPT code 87380 describes an immunoassay test to detect hepatitis D (delta agent) antigens, performed by a laboratory analyst. The service type is laboratory diagnostic testing (infectious disease serology). The typical site of service is a clinical laboratory or hospital laboratory where immunoassay-based serologic testing, such as enzyme immunoassay (EIA), is performed.
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