Summary & Overview
CPT 87467: Quantitative Hepatitis B Surface Antigen (HBsAg) Test
CPT code 87467 represents a quantitative laboratory test that measures hepatitis B surface antigen (HBsAg) levels in serum. This test is clinically important for monitoring chronic hepatitis B infection and for assessing antiviral therapy response. As an objective viral marker, quantitative HBsAg supports longitudinal patient management and can influence treatment strategy and follow-up intervals. Nationally, this test is performed across outpatient and hospital laboratory settings and is relevant to clinicians, laboratory administrators, and payers focused on infectious disease management and chronic liver care.
Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication provides a concise overview of clinical context, typical service lines, and payer coverage considerations. Readers will find benchmarks for utilization and reimbursement (where available), summaries of coding and billing practice considerations, and clinical context explaining when and why clinicians order a quantitative HBsAg assay. Data not available in the input is identified explicitly where applicable. The content is intended for a national audience of providers, billing professionals, and policy analysts seeking a clear, practice-focused description of CPT code 87467 and its role in hepatitis B management.
Billing Code Overview
CPT code 87467 describes a quantitative laboratory test for hepatitis B surface antigen (HBsAg) in a patient serum specimen. The assay measures the level of HBsAg to help clinicians monitor the course of chronic hepatitis B infection and assess potential response to antiviral therapy.
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Service type: Laboratory quantitative immunoassay
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Typical site of service: Clinical laboratory, hospital laboratory, or outpatient laboratory collection site
Clinical & Coding Specifications
Clinical Context
A 48-year-old patient with known chronic hepatitis B (HBV) attends a hepatology clinic for routine disease monitoring. The clinician orders quantification of hepatitis B surface antigen to assess viral activity and to inform decisions about antiviral therapy initiation or adjustment. A phlebotomy draw is performed in an outpatient laboratory at the clinic; the serum specimen is processed and analyzed by a clinical laboratory using a chemiluminescence immunoassay platform. Results are reported to the ordering provider and documented in the electronic medical record; abnormal changes prompt follow-up visits or medication review. Typical site of service is an outpatient clinic, hospital outpatient laboratory, or independent clinical laboratory.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier | Standard reporting when no specific modifier applies to the service. |
26 | Professional component | Use when only the professional interpretation/reporting component is billed separately from the technical component.
52 | Reduced services | Use when the test was partially performed or a reduced procedure was provided.
| Discontinued procedure | Use if testing was started but halted for patient-related or clinical reasons.