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    v1.0.30
    OpenPayerBilling CodesTransfusion Medicine ProceduresCPT cpt-86890-autologous-blood-collection-processing-storage
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    CPT 86890: Autologous Blood Collection, Processing, and Storage

    CPT code 86890 describes collection, processing, and storage of an autologous unit of blood or a blood component donated by a patient for anticipated future transfusion, typically performed as a predeposit autologous blood service prior to elective surgery; the service involves specialized handling and storage and is commonly provided in hospital-based blood bank or transfusion service settings or ambulatory surgical centers that manage preoperative autologous donations.

    For related coverage guidance, see recent payer policy updates: Hematology - Adzynma, Tumor Treating Fields for Pancreatic Cancer, Axicabtagene ciloleucel (Yescarta®) coverage.

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    Clinical & Coding Specifications

    Clinical Context

    A 56-year-old patient scheduled for elective total hip arthroplasty elects to predeposit autologous blood several weeks before surgery to reduce exposure to allogeneic transfusion. The patient presents to the hospital blood bank or transfusion service for collection visits. During each visit a licensed phlebotomist or transfusion medicine technologist performs donor screening, documents vital signs and hemoglobin, obtains informed consent, collects the specified unit(s) of whole blood or blood components, labels and processes the unit(s) per institutional protocols (including compatibility testing and component separation if indicated), and stores the unit(s) under controlled conditions until the anticipated operative date.

    Typical workflow steps:

    • Preoperative assessment and order entry by the surgeon or preadmission clinic.

    • Scheduling of autologous donation appointments with the blood bank.

    • Donor screening and collection visit(s) with documentation of eligibility and volume collected.

    • Processing, labeling, testing, and storage of autologous unit(s) according to regulatory standards.

    • Release and transfusion of the autologous unit(s) perioperatively as needed.

    Related Diagnoses

    ICD-10 CodeDescriptionClinical Relevance
    D50.0Iron deficiency anemia secondary to blood loss (chronic)May affect eligibility for autologous donation; screening required prior to collection
    D64.9Anemia, unspecifiedCommon comorbidity requiring assessment before predeposit autologous donation
    Z31.89Encounter for other procreative managementOccasionally used when planning for procedures with anticipated blood loss (contextual administrative use)
    Z48.81Encounter for surgical aftercare following other surgeryRelevant when autologous units are stored for future postoperative transfusion needs
    Z51.81Encounter for therapeutic drug level monitoringRepresents preoperative optimization encounters that may coincide with autologous donation planning
    Z90.4Acquired absence of blood components, transfusion historyRelevant to transfusion history documentation and planning for autologous units

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207P00000X
    282N00000X
    207L00000X
    363A00000X
    332B00000X
    1835P0200X
    246RH0600X
    1835C0207X

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    C50.919Malignant neoplasm of unspecified site of unspecified female breast
    C67.9Malignant neoplasm of bladder, unspecified
    C71.9Malignant neoplasm of brain, unspecified
    D50.9Iron deficiency anemia, unspecified
    D56.9Thalassemia, unspecified
    D63.0Anemia in neoplastic disease
    D64.9Anemia, unspecified
    G45.9Transient cerebral ischemic attack, unspecified
    G46.3Brain stem stroke syndrome

    Showing 1–10 of 27

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Hematology - AdzynmaCigna2026-10-15
    Tumor Treating Fields for Pancreatic Cancerselect_health2026-10-01
    Axicabtagene ciloleucel (Yescarta®) coverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Kentucky Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Kansas Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Idaho Only)UnitedHealthcare2026-10-01
    Brexucabtagene autoleucel (Tecartus) CoverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Pennsylvania Only)UnitedHealthcare2026-10-01
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Factor VIII ProductsCigna2026-09-15

    Related Codes

    CPT-86850-RBC-ANTIBODY-SCREENING

    CPT 86850: Screening Test for Non‑A/B Red Blood Cell Antibodies

    CPT-86860-RBC-ELUTION-IMMUNOHEMATOLOGY-BLOOD-BANK

    CPT 86860: RBC Elution for Antibody Detection

    CPT-86870-RBC-ANTIBODY-IDENTIFICATION-IMMUNOHEMATOLOGY

    CPT 86870: Antibody Identification to Red Blood Cells

    CPT-86880-DIRECT-ANTIGLOBULIN-TEST-DAT-COOMBS

    CPT 86880: Direct Antihuman Globulin (Coombs) Test

    CPT-86885-INDIRECT-ANTIGLOBULIN-COOMBS-TEST

    CPT 86885: Indirect Antiglobulin (Coombs) Test for Serum Antibodies

    CPT-86886-INDIRECT-ANTIGLOBULIN-COOMBS-TEST-SERIAL-DILUTIONS

    CPT 86886: Indirect Antihuman Globulin (Coombs) Test

    CPT-86891-INTRAOPERATIVE-BLOOD-SALVAGE-AUTOTRANSFUSION

    CPT 86891: Intraoperative Blood Salvage (Cell Salvage)

    CPT-86900-ABO-BLOOD-TYPING-SERUM-PLASMA

    CPT 86900: ABO Blood Typing Using Serum or Plasma

    CPT-86901-RH-BLOOD-GROUP-TYPING-SEROLOGIC-PLASMA-SERUM

    CPT 86901: Rh Blood Group Serologic Typing, Serum/Plasma

    CPT-86902-ANTIGEN-SCREENING-DONOR-BLOOD-UNIT

    CPT 86902: Antigen Screen of Donor Blood Unit

    Showing 1–10 of 38

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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