CPT code 86430 represents a laboratory serologic assay for rheumatoid factor (RF), a common biomarker used in evaluating suspected rheumatoid arthritis and related autoimmune disorders. Nationally, RF testing remains a routine diagnostic aid in rheumatology and primary care, supporting clinical diagnosis, disease characterization, and monitoring when combined with clinical evaluation and other tests. The code captures the laboratory technical work required to detect RF in patient serum.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The publication provides a concise reference for billing and clinical teams on how 86430 is classified and where the service is typically performed.

Readers will learn the clinical context for ordering RF testing, typical sites of service such as hospital and independent clinical laboratories, and operational considerations relevant to billing and coding workflows. Where specific data elements were not provided in the input, the summary notes that those items are not available. The piece is intended as a national-level overview for payers, providers, and coding professionals seeking clear, actionable information about CPT code 86430 and its role in laboratory diagnostics.