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CPT 86340: Intrinsic Factor Antibody Test
CPT code 86340 designates a serologic assay for intrinsic factor antibodies, a diagnostic test used to evaluate autoimmune gastritis and pernicious anemia by detecting antibodies that interfere with vitamin B12 absorption. Nationally, this test is clinically relevant for immunologic workups of unexplained macrocytic anemia and B12 deficiency and influences downstream diagnostic and treatment decisions.
Key payers addressed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. The analysis covers payer coverage considerations and common billing practices related to laboratory testing for intrinsic factor antibodies.
Readers will find a concise clinical context for CPT code 86340, typical sites of service, and an outline of billing details such as common modifiers. The publication summarizes what to expect in payer interactions, highlights common areas of coverage variation, and provides benchmarks and policy-relevant notes where available. Data not provided in the input are noted as unavailable.
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Billing Code Overview
CPT code 86340 describes a laboratory test that measures intrinsic factor antibodies in a patient specimen, typically blood. This assay is used in evaluating suspected autoimmune gastritis and pernicious anemia by detecting antibodies that target intrinsic factor, a protein required for vitamin B12 absorption.
Service Type: Serologic laboratory test
Typical Site of Service: Clinical laboratory or hospital laboratory, with specimen collection often performed in an ambulatory clinic or phlebotomy setting.
Data not available in the input for payers, associated taxonomies, ICD-10 diagnoses, and related codes.