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CPT 86141: High-Sensitivity C-Reactive Protein (hsCRP) Laboratory Test
CPT code 86141 represents the technical laboratory component for high-sensitivity C-reactive protein (hsCRP) testing, a widely used assay to assess systemic inflammation and stratify cardiovascular risk. Nationally, hsCRP testing is frequently ordered as part of preventive cardiology, risk assessment, and inflammatory disease evaluation, making accurate coding and billing for the technical component important for lab operations and payer adjudication. Key payers addressed in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.
Readers will find a concise overview of what CPT code 86141 covers, typical sites of service, and how this test fits into clinical workflows. The publication outlines common billing practices, relevant modifiers provided in the input, and operational benchmarks where available. It also summarizes clinical context for hsCRP testing and highlights considerations that affect lab reporting and payer processing. Data not available in the input is noted where applicable.
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Billing Code Overview
CPT code 86141 describes a laboratory technical procedure in which a lab analyst performs testing to measure high-sensitivity C-reactive protein (hsCRP) in a patient specimen, frequently serum. The service type is clinical laboratory testing — high-sensitivity CRP assay. The typical site of service is a clinical laboratory or hospital laboratory where trained laboratory personnel process and analyze blood specimens for cardiovascular risk assessment and inflammatory marker evaluation.
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