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    v1.0.30
    OpenPayerBilling CodesUrinalysis ProceduresCPT cpt-81020-microscopic-urinalysis-multiple-glass-collections
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    CPT 81020: Microscopic Urine Examination of Multiple Specimens

    CPT code 81020 describes a microscopic examination of two or three urine specimen containers (labeled glass 1, glass 2, and sometimes glass 3) performed by a laboratory analyst to identify and report cellular and bacterial elements; service type: urinalysis, microscopic examination of multiple specimens; typical site of service: clinical laboratory or hospital laboratory.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Clinical & Coding Specifications

    Clinical Context

    A 28-year-old female presents to an outpatient clinic with dysuria, urinary frequency, and suprapubic discomfort. Her primary care clinician collects three timed urine specimens (glass 1, glass 2, glass 3) over a single voiding episode for diagnostic evaluation. The specimens are labeled and sent to the clinical laboratory. A laboratory analyst performs microscopic examination of the two or three glass urine collections to evaluate for red blood cells, white blood cells, epithelial cells, casts, crystals, and bacterial forms and reports cellular and bacterial entities present. Results are routed back to the ordering clinician for correlation with urinalysis dipstick, urine culture, and clinical signs to guide treatment decisions. Typical workflow includes specimen accessioning, microscopic slide preparation, light microscopy review, documentation of findings in the laboratory information system, and transmission of the report to the ordering provider. Typical sites of service are hospital outpatient laboratories, independent clinical laboratories, and ambulatory clinic laboratories.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    81001Urinalysis, by dipstick or tablet reagent; automated, with microscopyOften performed before or alongside microscopic examination to screen for hematuria, pyuria, or nitrites.
    81002Urinalysis, by dipstick or tablet reagent; non-automated, without microscopyPoint-of-care screening that may prompt laboratory microscopic examination.
    81003Urinalysis, by dipstick or tablet reagent; non-automated, with microscopyAlternate urinalysis method that includes microscopic evaluation; may overlap with the lab's microscopy.
    87086Culture, bacterial; quantitative colony count, urinePerformed when microscopy suggests bacteriuria to identify organism and perform sensitivity testing.
    87205Smear, primary source with interpretation; Gram or other stain, bacterial smear, including direct microscopyPerformed when bacteria are observed on urine microscopy to provide stain-based organism characterization.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    207L00000X
    101YA0400X
    364SL0600X
    364SP0810X
    251300000X
    2080T0002X
    225400000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    E11.22Type 2 diabetes mellitus with diabetic chronic kidney disease
    E86.0Dehydration
    N10Acute pyelonephritis
    N13.6Pyonephrosis
    N20.0Calculus of kidney
    N20.1Calculus of ureter
    N20.2Calculus of kidney with calculus of ureter
    N30.00Acute cystitis without hematuria
    N30.01Acute cystitis with hematuria
    N30.90Cystitis, unspecified without hematuria

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-81000-URINALYSIS-DIP-STICK-AND-MICROSCOPIC-EXAM

    CPT 81000: Manual Urinalysis with Microscopy

    CPT-81001-URINALYSIS-DIPSTICK-OR-TABLET-REAGENT

    CPT 81001: Urinalysis by Dipstick or Tablet Reagent

    CPT-81002-MANUAL-URINALYSIS-REAGENT-STRIP-TABLET

    CPT 81002: Manual Urine Dipstick Chemical Analysis

    CPT-81003-AUTOMATED-URINE-DIPSTICK-ANALYSIS

    CPT 81003: Automated Urinalysis Dipstick with Instrumented Reader

    CPT-81005-URINE-ANALYTE-QUALITATIVE-SEMIQUANTITATIVE

    CPT 81005: Urine Qualitative or Semiquantitative Analyte Test

    CPT-81007-URINE-BACTERIURIA-NONCULTURE-NONDIPSTICK-TEST

    CPT 81007: Nonculture, Nondipstick Urinalysis for Bacteriuria

    CPT-81015-MICROSCOPIC-URINALYSIS-LABORATORY-EXAMINATION

    CPT 81015: Microscopic Urinalysis, Sediment Examination

    CPT-81025-URINE-PREGNANCY-TEST-VISUAL-READ

    CPT 81025: Urine Pregnancy Test, Analyst-Read Visual

    CPT-81050-TIMED-URINE-COLLECTION-VOLUME-MEASUREMENT

    CPT 81050: Timed Urine Volume Measurement

    CPT-81099-UNLISTED-URINE-PROCEDURE

    CPT 81099: Unlisted Urine Procedure

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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