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    v1.0.30
    OpenPayerBilling CodesUrinalysis ProceduresCPT cpt-81001-urinalysis-dipstick-or-tablet-reagent
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    CPT 81001: Urinalysis by Dipstick or Tablet Reagent

    CPT code 81001 represents a routine urinalysis performed by dipstick or tablet reagent methods to detect substances and cellular material (color, clarity, specific gravity, pH, protein, glucose, nitrites, WBC, ketones, etc.) associated with metabolic, kidney, and urinary tract disorders; service type: diagnostic urinalysis testing; typical site of service: outpatient clinic, physician office, urgent care, or other ambulatory care settings.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 28-year-old female presents to an outpatient primary care clinic with dysuria, urinary frequency, and mild suprapubic discomfort of 48 hours’ duration. The nurse obtains a clean-catch midstream urine specimen during the visit. A point-of-care dipstick urinalysis is performed to assess for leukocyte esterase, nitrites, blood, protein, glucose, ketones, specific gravity, pH, and color/clarity as part of the initial evaluation for suspected urinary tract infection (UTI). Results guide immediate clinical decision-making (e.g., empiric antibiotic selection, need for urine culture) and documentation in the electronic health record.

    Typical workflow:

    • Patient check-in and triage with symptom review and vital signs.

    • Specimen collection instruction and labeling of the urine sample.

    • Point-of-care dipstick urinalysis performed by nursing staff or medical assistant using reagent strips; results recorded in chart.

    • Clinician reviews urinalysis results with patient, documents findings, and determines next steps (patient education, urine culture if indicated, medication).

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    87086Culture, bacterial; quantitative colony count, urinePerformed when urinalysis suggests infection and a urine culture is required for organism identification and susceptibility testing.
    81002Urinalysis, by dipstick or tablet reagent for bilirubin, glucose, hemoglobin, ketones, leukocytes, nitrite; non-automated, with microscopyUsed for non-automated urinalysis procedures; sometimes listed when microscopy is also performed.
    81003Urinalysis; by reagent strip or tablet reagent, automated, without microscopyAutomated dipstick urinalysis alternative in higher-volume settings or analyzers.
    81025Urine pregnancy test, by visual color comparison methodsOften ordered alongside urinalysis in women of childbearing potential prior to treatment decisions.
    82565Urine creatinine, quantitativeUsed when assessment of renal function or urine concentration is required in conjunction with urinalysis.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    90Modifier ‑90 (Reference/Outside Laboratory) indicates that a laboratory test was performed by an entity other than the treating or reporting provider. The American Medical Association defines…- Use CPT modifier -90 when a laboratory test is performed by an outside/reference laboratory (an entity other than the treating or reporting physician or qualified professional) and the claim needs…
    91Modifier 91 — “Repeat Clinical Diagnostic Laboratory Test” — is appended when the exact same CPT laboratory test is performed more than once for the same patient on the same day because serial,…- Use modifier 91 when the exact same CPT laboratory test is performed more than once on the same patient on the same date because serial or repeated testing is medically necessary to monitor…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    95Modifier 95 indicates that a service was provided via synchronous, real‑time audio‑video telehealth rather than in‑person. Per CMS, AAPC and professional associations, append modifier 95 to claim…- Use modifier 95 to indicate a service was furnished via synchronous, real‑time audiovisual telehealth (a live audio‑video conference between patient and provider) rather than in‑person. - Pair…
    99Modifier 99 is a placeholder modifier used when more modifiers apply to a single procedure than the claim form or electronic field allows. The AMA classifies it under Provider Services and Ambulatory…- Use CPT modifier -99 when more modifiers apply to a single procedure line than the claim form or payer field allows (CMS/Noridian: when more than four modifiers are needed); append modifier 99 on…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207Q00000X
    207R00000X
    261QP2000X
    363L00000X
    207YS0012X
    372500000X
    163WC2100X
    163WM1400X

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    E10.9Type 1 diabetes mellitus without complications
    E11.9Type 2 diabetes mellitus without complications
    N10Acute pyelonephritis
    N11.0Nonobstructive reflux-associated chronic pyelonephritis
    N11.1Chronic obstructive pyelonephritis
    N11.8Other chronic tubulo-interstitial nephritis
    N18.4Chronic kidney disease, stage 4 (severe)
    N18.9Chronic kidney disease, unspecified
    N20.0Calculus of kidney
    N20.1Calculus of ureter

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-81000-URINALYSIS-DIP-STICK-AND-MICROSCOPIC-EXAM

    CPT 81000: Manual Urinalysis with Microscopy

    CPT-81002-MANUAL-URINALYSIS-REAGENT-STRIP-TABLET

    CPT 81002: Manual Urine Dipstick Chemical Analysis

    CPT-81003-AUTOMATED-URINE-DIPSTICK-ANALYSIS

    CPT 81003: Automated Urinalysis Dipstick with Instrumented Reader

    CPT-81005-URINE-ANALYTE-QUALITATIVE-SEMIQUANTITATIVE

    CPT 81005: Urine Qualitative or Semiquantitative Analyte Test

    CPT-81007-URINE-BACTERIURIA-NONCULTURE-NONDIPSTICK-TEST

    CPT 81007: Nonculture, Nondipstick Urinalysis for Bacteriuria

    CPT-81015-MICROSCOPIC-URINALYSIS-LABORATORY-EXAMINATION

    CPT 81015: Microscopic Urinalysis, Sediment Examination

    CPT-81020-MICROSCOPIC-URINALYSIS-MULTIPLE-GLASS-COLLECTIONS

    CPT 81020: Microscopic Urine Examination of Multiple Specimens

    CPT-81025-URINE-PREGNANCY-TEST-VISUAL-READ

    CPT 81025: Urine Pregnancy Test, Analyst-Read Visual

    CPT-81050-TIMED-URINE-COLLECTION-VOLUME-MEASUREMENT

    CPT 81050: Timed Urine Volume Measurement

    CPT-81099-UNLISTED-URINE-PROCEDURE

    CPT 81099: Unlisted Urine Procedure

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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