Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.30
    OpenPayerBilling CodesOther Diagnostic Nuclear Medicine ProceduresCPT cpt-78801-multi-day-multi-area-nuclear-medicine-imaging
    Ask Trek AI about this page

    CPT 78801: Multi-Day/Multi-Area Nuclear Medicine Tumor Localization

    Medicare pays $167 on average nationally for this procedure.

    CPT code 78801 describes diagnostic nuclear medicine imaging using a gamma-emitting radiotracer to localize tumors, inflammatory processes, or track radiopharmaceutical distribution when imaging involves either one or more days of scanning of two or more anatomic areas or two or more days of imaging of a single area; service type: multi-day nuclear medicine tumor/inflammatory localization study with vascular flow and blood pool imaging as indicated; typical site of service: hospital outpatient imaging department, nuclear medicine suite, or freestanding imaging center.

    For related coverage guidance, see recent payer policy updates: Vafseo (vadadustat) for anemia in CKD on dialysis, Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family Plans, Kerendia (finerenone) — Coverage Criteria.

    Customize your policy alerts

    Sign up for cpt 78801 policy alerts

    Get alerted when payer policies referencing 78801 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • Facility ComparisonBeds, revenue & payer mix
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A 62-year-old patient with a history of colorectal cancer presents with rising carcinoembryonic antigen (CEA) and focal bone pain. The oncology team orders radionuclide whole-body scintigraphic imaging using a gamma-emitting tracer to evaluate for metastatic disease. The study is planned as multi-day imaging because separate imaging of the abdomen/pelvis and the chest is required to localize suspected lesions and assess radiopharmaceutical distribution. The patient arrives at an outpatient nuclear medicine imaging center. A nuclear medicine physician reviews indications and allergies, injects the radiotracer, and documents time of administration. Imaging technologists acquire vascular flow, blood pool, and delayed static images over two or more days as indicated. The interpreting physician reviews multi-day images, correlates with prior CT and laboratory data, documents findings and impression, and issues a signed report for the referring oncologist. Typical sites of service include hospital outpatient radiology/nuclear medicine departments, freestanding imaging centers, and ambulatory surgical centers when required by clinical complexity.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    78800Radiopharmaceutical localization of tumor or distribution; planar imaging of one area, single dayPerformed when only a single anatomic area is imaged in one day; 78801 represents multi-area or multi-day extensions.
    78803Tumor imaging; SPECT including iterative reconstruction, if performedUsed when single-photon emission computed tomography is added to planar imaging for improved lesion localization.
    78306Thyroid uptake and/or imaging, diagnosticPerformed when specific organ-targeted scintigraphy (thyroid) is required; different radiopharmaceutical and protocol but same nuclear medicine workflow.
    78451Myocardial SPECT; single study, perfusion imaging (multiple studies exist)Performed when cardiac perfusion or gated blood pool imaging is part of the evaluation of cardiac function included in the exam.
    79005Radiopharmaceutical localization of tumor; qualitative imaging, single dayUsed for qualitative whole-body or limited imaging protocols; complements multi-day protocols when preliminary images are obtained.

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207R00000X
    363A00000X
    363L00000X
    261QU0200X
    305S00000X
    363LW0102X
    207PS0010X
    207ND0101X

    Related Payer Policy Updates

    Specialty: Nephrology1 / 3

    10 rows

    PolicyPayerEffective Date
    Vafseo (vadadustat) for anemia in CKD on dialysisCigna2026-08-15
    Metabolic Disorders - Cysteamine (Oral) Products for Individual and Family PlansCigna2026-08-15
    Kerendia (finerenone) — Coverage CriteriaBlue Cross Blue Shield - Iowa2026-08-05
    Voyxact (sibeprenlimab-szsl) — Prior authorization / medical necessity for primary IgA nephropathyColorado Rocky Mountain Health Plans2026-08-01
    Oxlumo (lumasiran) and Rivfloza (nedosiran) — Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Korsuva (difelikefalin) — Medical Benefit Drug Coverage Criteria (Ohio)Colorado Rocky Mountain Health Plans2026-08-01
    Complement Inhibitors - EmpaveliCigna2026-08-01
    Tolvaptan (Jynarque)Cigna2026-08-01
    Nephrology - Filspari (sparsentan) coverageCigna2026-08-01
    Rivfloza (nedosiran) prior authorization for PH1UnitedHealthcare2026-08-01

    Related Codes

    CPT-78800-PLANAR-NUCLEAR-MEDICINE-SINGLE-AREA-TUMOR-LOCALIZATION

    CPT 78800: Planar Nuclear Medicine Imaging, Single Area

    CPT-78802-WHOLE-BODY-NUCLEAR-MEDICINE-IMAGING

    CPT 78802: Whole-Body Nuclear Medicine Imaging for Tumor/Inflammation Localization

    CPT-78803-SPECT-SINGLE-AREA-LOCALIZATION

    CPT 78803: Single-Day SPECT Tumor/Tracer Localization

    CPT-78804-MULTIDAY-WHOLE-BODY-NUCLEAR-IMAGING-GAMMA-TRACER

    CPT 78804: Whole-Body Nuclear Medicine Imaging, Multi-Day

    CPT-78808-RADIOTRACER-INJECTION-GAMMA-PROBE-LOCALIZATION

    CPT 78808: Radioguided Localization with Intravenous Radiotracer

    CPT-78811-TARGETED-PET-LOCALIZED-BODY-REGION

    CPT 78811: PET, limited area imaging

    CPT-78812-FDG-PET-BODY-IMAGING-FOR-ONCOLOGIC-EVALUATION

    CPT 78812: FDG PET Imaging for Detection of Malignant Tumors

    CPT-78813-WHOLE-BODY-PET

    CPT 78813: PET Whole Body Scan

    CPT-78814-PET-CT-TUMOR-LOCALIZATION-METABOLIC-EVALUATION

    CPT 78814: PET/CT Tumor Localization and Metabolic Imaging

    CPT-78815-PET-CT-TUMOR-IMAGING-ANATOMICAL-LOCALIZATION

    CPT 78815: PET/CT Tumor Imaging with Anatomical Localization

    Showing 1–10 of 16

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.