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    v1.0.30
    OpenPayerBilling CodesDiagnostic Nuclear Medicine Procedures on the Nervous SystemCPT cpt-78630-csf-flow-study-hydrocephalus-leak-evaluation
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    CPT 78630: Cerebrospinal Fluid (CSF) Flow Study, Head

    Medicare pays $205 on average nationally for this procedure.

    CPT code 78630 describes a cerebrospinal fluid (CSF) flow study of the head, a diagnostic imaging procedure used to evaluate CSF dynamics to help detect CSF leaks and assess for hydrocephalus; service type: diagnostic CSF flow assessment; typical site of service: hospital outpatient imaging or radiology suite where specialized CSF flow imaging (often MRI-based) is performed.

    For related coverage guidance, see recent payer policy updates: Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM), Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®), Lumbar Microdiscectomy.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult referred to neuroradiology for evaluation of suspected cerebrospinal fluid (CSF) flow abnormality. The patient presents with progressive gait disturbance, cognitive decline, and urinary incontinence suggesting possible normal pressure hydrocephalus, or with clear rhinorrhea after head trauma or skull base surgery raising concern for a CSF leak. The clinical workflow begins with a neurologic or neurosurgical evaluation and brain imaging (CT or MRI) to assess ventricular size and exclude mass lesion. When CSF flow dynamics need clarification, the provider orders a radionuclide cisternography study coded as 78630. On the day of service, the patient receives lumbar intrathecal injection of radiotracer by a qualified physician or advanced practice provider in a procedure room or interventional suite. Dynamic and delayed planar and/or SPECT images of the head (and sometimes spine) are obtained over several hours to document tracer transit, ventricular reflux, or extracranial tracer leakage. The interpreting physician reviews images, documents findings (e.g., tracer accumulation in paranasal sinuses for leak or delayed cortical transit for hydrocephalus), and issues a diagnostic report to the referring clinician. Typical sites of service include hospital radiology departments, outpatient imaging centers, and designated nuclear medicine suites. Common patient monitoring includes vital signs, neurologic checks, and precautions to minimize post‑procedural headache or infection risk.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    62270Spinal puncture, lumbar, diagnosticOften performed to obtain CSF or administer intrathecal radiotracer prior to 78630
    78800Radiopharmaceutical localization of tumor or distribution of radiopharmaceutical (planar)Related nuclear medicine imaging techniques; alternative radionuclide study formats
    70553Magnetic resonance (MR) of brain with and without contrastOften obtained before or after to assess ventricular anatomy and alternative causes of symptoms
    70100CT head without contrastInitial imaging to evaluate acute causes or surgical anatomy prior to cisternography
    99354Prolonged evaluation and management servicesCan be reported by the physician if prolonged face-to-face time is required for complex pre‑procedure counseling or interpretation (use per payer rules)

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    27Modifier 27 indicates a separate, subsequent outpatient hospital E/M service provided to the same patient on the same date by a different provider in a hospital outpatient setting. It is a…- Use modifier -27 on facility (hospital outpatient/ambulatory service center) claims to report a subsequent, separate, and distinct outpatient E/M service provided to the same patient on the same…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RH0000X
    208000000X
    363A00000X
    101YM0800X
    152WP0200X
    2080P0202X
    3336C0004X
    207U00000X

    Related Payer Policy Updates

    Specialty: Neurology/Neurosurgery1 / 2

    10 rows

    PolicyPayerEffective Date
    Clinical Review Criteria Intraoperative Neurophysiological Monitoring (IONM)Kaiser Permanente2027-01-01
    Remote Electrical Neuromodulation for Migraines (i.e., Nerivio®)bcbsvermont2026-11-01
    Lumbar Microdiscectomyuniverahealthcare2026-10-15
    Artificial Cervical Intervertebral Discuniverahealthcare2026-10-15
    Lumbar Decompressionuniverahealthcare2026-10-15
    Responsive Neurostimulation for Focal EpilepsyPremera Bluecross2026-10-14
    Intraoperative MonitoringProvidence Health Plan2026-10-01
    Intraoperative MonitoringProvidence Health Plan2026-10-01
    High-Intensity Focused UltrasoundMass General Brigham Health Plan2026-10-01
    Vagal Nerve StimulationAmbetter Nevada2026-10-01

    Related Codes

    CPT-78600-BRAIN-NUCLEAR-STATIC-IMAGING-FEWER-THAN-FOUR-VIEWS

    CPT 78600: Nuclear Diagnostic Brain Imaging, <4 Static Views

    CPT-78601-BRAIN-NUCLEAR-PERFUSION-IMAGING-FEWER-THAN-FOUR-STATIC-VIEWS

    CPT 78601: Nuclear Diagnostic Brain Imaging, Static Views and Flow

    CPT-78605-BRAIN-NUCLEAR-STATIC-IMAGING-FOUR-OR-MORE-VIEWS

    CPT 78605: Brain Nuclear Diagnostic Imaging, Four+ Static Views

    CPT-78606-NUCLEAR-BRAIN-IMAGING-STATIC-VIEWS-CEREBRAL-BLOOD-FLOW

    CPT 78606: Brain Nuclear Imaging, Static Views with Flow Evaluation

    CPT-78608-PET-BRAIN-METABOLIC-IMAGING

    CPT 78608: Brain PET for Cerebral Metabolic Imaging

    CPT-78609-PET-BRAIN-IMAGING

    CPT 78609: Brain PET Scan for Function and Perfusion

    CPT-78610-CEREBRAL-PERFUSION-NUCLEAR-MEDICINE-STUDY

    CPT 78610: Brain Perfusion Study with Gamma Tracer

    CPT-78635-CSF-FLOW-VENTRICULAR-IMAGING-HYDROCEPHALUS

    CPT 78635: CSF Flow Study for Ventricular Assessment

    CPT-78645-CSF-SHUNT-FLOW-IMAGING

    CPT 78645: CSF Shunt Patency and Flow Imaging Study

    CPT-78650-CSF-LEAK-NUCLEAR-IMAGING-LOCALIZATION

    CPT 78650: Nuclear Medicine Localization of CSF Leak

    Showing 1–10 of 12

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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