Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesDiagnostic Nuclear Medicine Procedures on the Gastrointestinal SystemCPT cpt-78267-c14-urea-breath-test-helicobacter-pylori
    Ask Trek AI about this page

    CPT 78267: C-14 Urea Breath Test for Helicobacter pylori

    CPT code 78267 describes administration of a radioactive carbon-14 (C–14) labeled urea solution to the patient to diagnose Helicobacter pylori infection of the stomach; the service is a diagnostic breath test performed in an outpatient clinic or ambulatory diagnostic setting to detect bacterial urease activity by measuring labeled carbon dioxide in exhaled breath.

    For related coverage guidance, see recent payer policy updates: Esophagogastroduodenoscopy (EGD) Coverage Policy, Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD), Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant Testing.

    Customize your policy alerts

    Sign up for cpt 78267 policy alerts

    Get alerted when payer policies referencing 78267 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 7

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old adult presents to an outpatient nuclear medicine clinic with a several-week history of dyspepsia, epigastric pain, and suspected peptic ulcer disease after failed empirical therapy. The gastroenterologist orders a noninvasive urea breath test using a C-14 labeled urea solution to detect active Helicobacter pylori infection. The patient fasts for the required pretest interval, and medications that interfere with H. pylori testing (proton-pump inhibitors, antibiotics, bismuth) are held per protocol. At arrival, the nuclear medicine technologist reviews indications and consent, administers the C-14 urea solution orally, and collects exhaled breath samples at specified intervals for radioactivity measurement. The physician interprets the results and documents presence or absence of H. pylori infection. Typical sites of service are outpatient radiology/nuclear medicine or hospital outpatient clinic. The service type is a diagnostic nuclear medicine test with specimen collection via breath sampling and radioactive tracer administration.

    Related Diagnoses

    ICD-10 CodeDescriptionClinical Relevance
    K29.70Gastritis, unspecified, without bleedingGastritis symptoms often prompt testing for H. pylori as an etiologic agent.
    K29.50Gastritis, unspecified, with unspecified bleedingActive gastritis/bleeding may require diagnosis of H. pylori to guide therapy.
    K25.9Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforationPeptic ulcer disease commonly linked to H. pylori infection; testing guides eradication therapy.
    R10.13Epigastric painNon-specific symptom leading to evaluation for H. pylori when dyspepsia is present.
    K21.9Gastro-esophageal reflux disease without esophagitisGERD may prompt dyspepsia evaluation including H. pylori testing when indicated.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    2080P0207XPediatric Hematology & Oncology PhysicianA pediatrician trained in the combination of pediatrics, hematology and oncology to recognize and manage pediatric blood disorders and cancerous disea…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    207PH0002XHospice and Palliative Medicine (Emergency Medicine) PhysicianAn emergency medicine physician with special knowledge and skills to prevent and relieve the suffering experienced by patients with life-limiting illn…
    235Z00000XSpeech-Language PathologistThe speech-language pathologist is the professional who engages in clinical services, prevention, advocacy, education, administration, and research in…
    225000000XOrthotic FitterAn individual trained in the management of fitting prefabricated orthoses.
    374700000XTechnician(1) A person with specialized training in a narrow field of expertise whose occupation requires training and is skilled in specific technical processe…
    2080S0010XPediatric Sports Medicine PhysicianA pediatrician who is responsible for continuous care in the field of sports medicine, not only for the enhancement of health and fitness, but also fo…

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    E86.0Dehydration
    K21.9Gastro-esophageal reflux disease without esophagitis
    K25.9Gastric ulcer, unspecified as acute or chronic, without hemorrhage or perforation
    K26.9Duodenal ulcer, unspecified as acute or chronic, without hemorrhage or perforation
    K27.9Peptic ulcer, site unspecified, unspecified as acute or chronic, without hemorrhage or perforation
    K29.00Acute gastritis without bleeding
    K29.30Chronic superficial gastritis without bleeding
    K29.40Chronic atrophic gastritis without bleeding
    K29.50Unspecified chronic gastritis without bleeding
    K29.60Other gastritis without bleeding

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    7 rows

    PolicyPayerEffective Date
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01
    Celiac Disease TestingOscar Health2026-10-01

    Related Codes

    CPT-78201-LIVER-SPLEEN-SCAN-DIAGNOSTIC-NUCLEAR-MEDICINE

    CPT 78201: Liver and Spleen Scan

    CPT-78202-LIVER-SPLEEN-SCAN-NUCLEAR-MEDICINE

    CPT 78202: Liver and Spleen Scan

    CPT-78215-LIVER-SPLEEN-SCAN-NUCLEAR-MEDICINE

    CPT 78215: Liver and Spleen Scan, Diagnostic Nuclear Medicine

    CPT-78216-LIVER-SPLEEN-SCAN-DIAGNOSTIC-IMAGING

    CPT 78216: Liver and Spleen Scan

    CPT-78226-HEPATOBILIARY-SCINTIGRAPHY-HEPATOBILIARY-IMAGING

    CPT 78226: Hepatobiliary Scintigraphy (Hepatobiliary Imaging)

    CPT-78227-HEPATOBILIARY-SCINTIGRAPHY-LIVER-BILE-GALLBLADDER-IMAGING

    CPT 78227: Hepatobiliary (Cholescintigraphy) Scan

    CPT-78230-SALIVARY-GLAND-NUCLEAR-IMAGING

    CPT 78230: Salivary Gland Imaging with Radiotracer

    CPT-78231-SALIVARY-GLAND-NUCLEAR-IMAGING-SERIAL-IMAGES

    CPT 78231: Salivary Gland Scintigraphy, Serial Imaging

    CPT-78232-SALIVARY-GLAND-SCINTIGRAPHY-PAROTID-FUNCTION

    CPT 78232: Salivary Gland Scintigraphy (Parotid Gland Scan)

    CPT-78258-ESOPHAGEAL-TRANSIT-SCINTIGRAPHY-ESOPHAGEAL-MOTILITY-STUDY

    CPT 78258: Esophageal Transit Scintigraphy

    Showing 1–10 of 21

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.