Summary & Overview
CPT 77407: 3D CRT/IMRT Radiation Therapy, Single Isocenter, Level 2
CPT code 77407 represents advanced external beam radiation therapy at level 2 complexity, including three–dimensional conformal radiation therapy (3D CRT) and intensity modulated radiation therapy (IMRT) delivered to a single isocenter. This code captures more complex beam arrangements and conformal targeting than basic 2D delivery and may include imaging guidance when performed. It is nationally relevant because it denotes a common, higher-complexity radiation delivery level used across oncology care settings and influences procedural categorization and billing for radiation therapy services.
Key payers covered in the analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise benchmarking and policy-oriented overview that outlines how this service is classified, typical sites of service, and the clinical context for 3D CRT and IMRT at a single isocenter. The publication reviews coding definitions and service characteristics, summarizes common billing modifiers and payer considerations (where available), and situates 77407 within radiation oncology service lines.
This summary is intended for national audiences including health plan analysts, billing professionals, and oncology practice administrators who need a clear, policy-focused reference to the code and its clinical role. Data not available in the input will be noted where applicable in detailed sections.
Billing Code Overview
CPT code 77407 describes radiation therapy delivered at level 2 complexity, encompassing three–dimensional conformal radiation therapy (3D CRT) and intensity modulated radiation therapy (IMRT) delivered to a single isocenter. The code covers delivery that involves more complex beam arrangements and conformal targeting than basic 2D techniques, and the billed service may include imaging guidance when performed.
Service type: Advanced external beam radiation therapy (3D CRT / IMRT) at single isocenter, level 2 complexity
Typical site of service: Hospital outpatient radiation oncology departments and freestanding radiation therapy centers
Clinical & Coding Specifications
Clinical Context
A 64-year-old patient with a newly diagnosed, localized prostate adenocarcinoma is referred to radiation oncology for definitive external beam radiation. After multidisciplinary review, the patient undergoes treatment planning including simulation CT with immobilization, contouring of target volumes and organs at risk, and creation of an intensity modulated radiation therapy (IMRT) plan delivered to a single isocenter. Daily image guidance (cone-beam CT or kV imaging) is used for setup verification. The clinical workflow includes simulation and fiduciary or soft-tissue localization, physics plan quality assurance, daily treatment delivery sessions over several weeks, on-treatment visits for toxicity assessment, and periodic follow-up visits to assess response and late effects. The typical site of service is an outpatient radiation oncology clinic or hospital-based radiation therapy department equipped with linear accelerators capable of 3D conformal radiation therapy or IMRT and image-guidance systems.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
26 | Professional component | When billing separately for the physician’s interpretation/planning component of the radiation therapy service when technical equipment is billed by another entity |
TC |