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    OpenPayerBilling CodesBreast, MammographyCPT cpt-77065-diagnostic-breast-imaging-computer-aided-detection
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    CPT 77065: Diagnostic Mammography of One Breast with CAD

    Medicare pays $86 on average nationally for this procedure.

    CPT code 77065 describes diagnostic X‑ray imaging of one breast for evaluation of a known lump or suspected cancer, using digital image acquisition and computer-assisted image analysis to help identify potential abnormalities; service type: diagnostic mammographic imaging with computer-aided detection, typical site of service: outpatient imaging center, breast center, or hospital radiology department.

    For related coverage guidance, see recent payer policy updates: Abortion Services, Prolonged Services for Labor Management, Prolonged Services for Labor Management.

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old woman presents to a breast imaging center with a palpable left breast mass felt on self-examination. The patient has localized breast tenderness and focal skin dimpling on exam. The referring clinician orders targeted diagnostic mammographic imaging of the left breast using computer-aided detection/diagnostic software to assist interpretation. The radiology workflow includes patient registration, review of prior imaging if available, positioning for spot compression and magnification views, acquisition of diagnostic full-field mammographic images of the affected breast (77065 describes imaging of a single breast for a known lump or suspected cancer with use of software that converts signals into digital data and analyzes images). The technologist documents laterality and views obtained; the interpreting radiologist reviews images, correlated clinical findings, and generates a diagnostic report with BI-RADS assessment and recommended next steps (ultrasound, biopsy, or short-interval follow-up). Image sequence, technical factors, and use of CAD/AI software are documented in the report and technical record for billing and quality assurance. Typical site of service is an outpatient radiology department, breast imaging center, or ambulatory imaging clinic. The service type is diagnostic targeted mammography with computer-assisted image analysis for a single breast.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    77066Diagnostic mammography, bilateral (two-view study of each breast), including computer-aided detection when performedPerformed when both breasts require diagnostic imaging; 77065 is unilateral equivalent when only one breast is imaged
    77067Screening mammography, bilateral (two-view study of each breast), including computer-aided detection when performedScreening exam that may precede diagnostic mammography if an abnormality is first suspected on screening
    76641Ultrasound, breast, unilateral, real time with image documentation, including axilla when performed; completeOften performed immediately after diagnostic mammography (77065) to characterize a palpable mass or correlate a suspicious finding
    19083Biopsy, breast, with placement of breast localization device(s) when performed (e.g., clip), percutaneous, using imaging guidancePerformed after diagnostic imaging if lesion requires tissue diagnosis; imaging guides targeting
    76098Breast mammography for lesion localization and/or surgical guidance (e.g., preoperative needle localization), unilateralUsed when a lesion identified on 77065 requires preoperative localization prior to surgical excision
    76942Ultrasonic guidance for needle placement (eg, biopsy, aspiration, injection, localization device)Used to guide percutaneous breast biopsies or localizations following diagnostic imaging

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RC0000X
    246ZN0300X
    246QB0000X
    363LP0808X
    103TB0200X
    171W00000X
    261QP0904X
    207Q00000X

    Related Payer Policy Updates

    Specialty: Obstetrics/Gynecology1 / 3

    10 rows

    PolicyPayerEffective Date
    Abortion ServicesNew Mexico Health Care Authority2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Prolonged Services for Labor ManagementPremera Bluecross2027-01-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesPremera Bluecross2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesPremera Bluecross2026-10-01
    Maternal Serum Testing for Prediction of Adverse Obstetric OutcomesBlue Cross Blue Shield - Massachusetts2026-10-01
    Cervical Cancer ScreeningOscar Health2026-10-01
    Prenatal Testing for Fetal AneuploidyOscar Health2026-10-01
    Diagnosis of VaginitisOscar Health2026-10-01
    Prenatal Screening (Nongenetic)Oscar Health2026-10-01

    Related Codes

    CPT-77046-BREAST-MRI-NON-CONTRAST-SINGLE-BREAST-3D

    CPT 77046: Unilateral Non-Contrast Breast MRI, 3-D Imaging

    CPT-77047-BREAST-MRI-NON-CONTRAST-BILATERAL

    CPT 77047: Bilateral Breast MRI, Non-Contrast 3D Imaging

    CPT-77048-BREAST-MRI-SINGLE-BREAST-CONTRAST-3D

    CPT 77048: Breast MRI, Single Breast, With and Without Contrast

    CPT-77049-BREAST-MRI-WITH-AND-WITHOUT-CONTRAST-BILATERAL

    CPT 77049: Bilateral Breast MRI, 3D With and Without Contrast

    CPT-77053-DUCTOGRAM-RADIOLOGICAL-SUPERVISION-INTERPRETATION-SINGLE-DUCT

    CPT 77053: Ductogram (Galactogram), Single Duct Radiology

    CPT-77054-DUCTOGRAM-GALACTOGRAM-MULTIPLE-DUCTS-RADIOLOGICAL-INTERPRETATION

    CPT 77054: Ductogram (Galactogram), Radiologic Supervision & Interpretation

    CPT-77061-DIGITAL-TOMOSYNTHESIS-ONE-BREAST-DIAGNOSTIC

    CPT 77061: Diagnostic Digital Tomosynthesis of One Breast

    CPT-77062-DIGITAL-BREAST-TOMOSYNTHESIS-BILATERAL-DIAGNOSTIC

    CPT 77062: Digital Tomosynthesis of Bilateral Breasts for Diagnostic Evaluation

    CPT-77063-DIGITAL-BREAST-TOMOSYNTHESIS-3D-MAMMOGRAPHY

    CPT 77063: Breast Tomosynthesis (3D Mammography)

    CPT-77066-DIAGNOSTIC-BILATERAL-MAMMOGRAPHY-WITH-CAD

    CPT 77066: Diagnostic Digital Breast Tomosynthesis for Suspected Cancer

    Showing 1–10 of 11

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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