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    v1.0.28
    OpenPayerBilling CodesDiagnostic Radiology (Diagnostic Imaging) Procedures of the Gastrointestinal TractCPT cpt-74300-intraoperative-cholangiography-imaging-supervision-interpretation
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    CPT 74300: Intraoperative Cholangiography, Imaging S&I

    Medicare pays $13 on average nationally for this procedure.

    CPT code 74300 describes imaging supervision and interpretation of cholangiography performed during surgery with injection of contrast into the common bile duct to detect stones, strictures, or tumors; the service represents imaging supervision and interpretation (S&I) and is typically provided intraoperatively in an operating room or other surgical suite setting as part of biliary tract operative procedures.

    For related coverage guidance, see recent payer policy updates: Esophagogastroduodenoscopy (EGD) Coverage Policy, Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD), Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant Testing.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 56-year-old patient undergoing an open or laparoscopic cholecystectomy has intraoperative cholangiography to assess for choledocholithiasis or biliary obstruction. The surgeon cannulates the common bile duct and injects iodinated contrast while a radiology provider or an appropriately credentialed physician supervises and interprets fluoroscopic images in real time to identify filling defects, strictures, or extravasation. The imaging supervision and interpretation are documented separately from the surgical procedure; the interpreting provider records findings, time of service, contrast type, and any additional imaging maneuvers performed. If stones or obstruction are identified, the surgical team may proceed with duct exploration, stone extraction, stent placement, or postoperative planning based on the interpreted images.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    47562Laparoscopic cholecystectomy with cholangiography, when performedCommon primary surgical procedure during which intraoperative cholangiography occurs; surgeon performs cystic duct cannulation and contrast injection.
    47563Laparoscopic cholecystectomy with common duct exploration, with or without T-tubePerformed if stones are identified on the cholangiogram and the surgeon proceeds to explore and clear the common bile duct.
    74301Cholangiography, diagnostic; percutaneousRadiographic cholangiography via percutaneous approach — alternative technique for biliary imaging in other clinical contexts.
    47590Exploration of common bile ductSurgical code for open or laparoscopic exploration of the common bile duct often following positive intraoperative cholangiography.
    76000Fluoroscopic guidance for needle placement (eg, biopsy, aspiration, injection)Fluoroscopic assistance codes that may be reported when additional fluoroscopic guidance services are provided in the course of biliary interventions.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    57CPT® modifier -57 (“Decision for Surgery”) is appended to an Evaluation and Management (E/M) service when that encounter results in the initial decision to perform a major surgery (a procedure with a…- Use modifier 57 when an E/M service provided by the same provider (or same tax ID) on the day of or the day before a major surgical procedure (90‑day global period) results in the initial decision…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    207P00000XEmergency Medicine PhysicianAn emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
    207RP1001XPulmonary Disease PhysicianAn internist who treats diseases of the lungs and airways. The pulmonologist diagnoses and treats cancer, pneumonia, pleurisy, asthma, occupational an…
    207RH0000XHematology (Internal Medicine) PhysicianAn internist with additional training who specializes in diseases of the blood, spleen and lymph. This specialist treats conditions such as anemia, cl…
    163WP0200XPediatric Registered NurseNursing Service Providers · Registered Nurse
    374U00000XHome Health AideA person trained to assist public health nurses, home health nurses, and other health professionals in the bedside care of patients in their homes.
    315P00000XIntellectual Disabilities Intermediate Care FacilityAn intermediate care facility providing services for individuals with intellectual disabilities.
    163WP0808XPsychiatric/Mental Health Registered NurseNursing Service Providers · Registered Nurse
    252Y00000XEarly Intervention Provider AgencyEarly intervention services are an effective way to address the needs of infants and toddlers who have developmental delays or disabilities. The servi…

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    7 rows

    PolicyPayerEffective Date
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01
    Celiac Disease TestingOscar Health2026-10-01

    Related Codes

    CPT-74210-PHARYNX-CERVICAL-ESOPHAGUS-CONTRAST-STUDY

    CPT 74210: Radiologic Exam of Pharynx and Cervical Esophagus with Contrast

    CPT-74220-ESOPHAGRAM-FLUOROSCOPIC-BARIUM-SWALLOW

    CPT 74220: Fluoroscopic Esophagram (Barium Swallow)

    CPT-74221-DOUBLE-CONTRAST-ESOPHAGRAM-BARIUM-EFFERVESCENT

    CPT 74221: Double-Contrast Esophagram with Barium and Effervescent Agent

    CPT-74230-VIDEOFLUOROSCOPIC-SWALLOW-STUDY

    CPT 74230: Videofluoroscopic Swallowing Study

    CPT-74235-ESOPHAGEAL-FOREIGN-BODY-REMOVAL-IMAGING-INTERPRETATION

    CPT 74235: Imaging Supervision for Esophageal Foreign Body Removal

    CPT-74240-UPPER-GASTROINTESTINAL-SERIES-BARIUM-CONTRAST

    CPT 74240: Upper Gastrointestinal Barium Contrast Study

    CPT-74246-UPPER-GI-DOUBLE-CONTRAST-FLUOROSCOPY

    CPT 74246: Upper GI Series with Air and High-Density Barium

    CPT-74248-SMALL-INTESTINE-FOLLOW-THROUGH-AFTER-UPPER-GASTROINTESTINAL-STUDY

    CPT 74248: Small Intestine Follow-Through, Multiple Series

    CPT-74250-SMALL-BOWEL-SINGLE-CONTRAST-BARIUM-STUDY

    CPT 74250: Small Bowel Single‑Contrast Barium Study

    CPT-74251-SMALL-BOWEL-DOUBLE-CONTRAST-ENTERIC-RADIOGRAPHY

    CPT 74251: Small Bowel Double-Contrast Enteroclysis

    Showing 1–10 of 25

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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