Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.30
    OpenPayerBilling CodesDiagnostic Radiology (Diagnostic Imaging) Procedures of the Gastrointestinal TractCPT cpt-74251-small-bowel-double-contrast-enteric-radiography
    Ask Trek AI about this page

    CPT 74251: Small Bowel Double-Contrast Enteroclysis

    Medicare pays $239 on average nationally for this procedure.

    CPT code 74251 describes a double-contrast enteroclysis study of the small intestine in which high-density barium and air are instilled through a nasogastric or oroduodenal tube with a scout film (if performed) and sequential radiographic exposures; this is an imaging procedure typically performed in a radiology department or hospital outpatient setting and may include IV infusion of glucagon when administered prior to the exam.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

    Customize your policy alerts

    Sign up for cpt 74251 policy alerts

    Get alerted when payer policies referencing 74251 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • Facility ComparisonBeds, revenue & payer mix
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A 48-year-old patient presents with chronic intermittent abdominal pain, unexplained weight loss, and intermittent melena despite negative upper endoscopy and colonoscopy. The gastroenterologist orders a double-contrast small bowel follow-through with enteric intubation to evaluate for Crohn disease, small-bowel neoplasm, or subtle mucosal ulceration. The patient arrives to the radiology suite fasting; an initial scout radiograph is obtained. A nasoenteric tube is advanced under fluoroscopic guidance through the nose, past the stomach, and into the duodenum or proximal jejunum. High-density barium is infused through the tube followed by room air (double-contrast technique). Sequential fluoroscopic spot radiographs and timed radiographs of the small intestine are obtained to evaluate mucosal pattern, strictures, or mass effect. Intravenous glucagon may be administered prior to contrast instillation to reduce bowel motility. The procedure is typically performed in an outpatient radiology department or hospital imaging suite with monitoring by radiology technologists and a radiologist for interpretation; sedation is uncommon. Images are processed and a diagnostic radiology report is generated and routed to the referring gastroenterologist for further management decisions.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    74240Upper gastrointestinal, contrast study, including esophagus, stomach, and small intestine when performedPerformed when combined evaluation of esophagus/stomach and small bowel is needed; may precede or be an alternative to 74251
    74250Small bowel follow-through; radiological supervision and interpretationSimilar small-bowel evaluation but without enteric intubation and double-contrast technique; alternative technique in the diagnostic algorithm
    74260Enteroclysis, radiological supervision and interpretationClosely related; some sources use 74251 for double-contrast enteroclysis while 74260 may describe similar procedures — included for workflow context
    96100Neurobehavioral status exam (clinical test)Data not typically associated (included only if neuro assessment is needed)
    99143Anesthesia for procedures on the gastrointestinal tractUsed if anesthesia services are required for patient comfort or safety during tube placement or procedure

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363L00000X
    1223G0001X
    3336C0002X
    317400000X
    302R00000X
    363LX0106X
    332U00000X
    1835C0205X

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-74210-PHARYNX-CERVICAL-ESOPHAGUS-CONTRAST-STUDY

    CPT 74210: Radiologic Exam of Pharynx and Cervical Esophagus with Contrast

    CPT-74220-ESOPHAGRAM-FLUOROSCOPIC-BARIUM-SWALLOW

    CPT 74220: Fluoroscopic Esophagram (Barium Swallow)

    CPT-74221-DOUBLE-CONTRAST-ESOPHAGRAM-BARIUM-EFFERVESCENT

    CPT 74221: Double-Contrast Esophagram with Barium and Effervescent Agent

    CPT-74230-VIDEOFLUOROSCOPIC-SWALLOW-STUDY

    CPT 74230: Videofluoroscopic Swallowing Study

    CPT-74235-ESOPHAGEAL-FOREIGN-BODY-REMOVAL-IMAGING-INTERPRETATION

    CPT 74235: Imaging Supervision for Esophageal Foreign Body Removal

    CPT-74240-UPPER-GASTROINTESTINAL-SERIES-BARIUM-CONTRAST

    CPT 74240: Upper Gastrointestinal Barium Contrast Study

    CPT-74246-UPPER-GI-DOUBLE-CONTRAST-FLUOROSCOPY

    CPT 74246: Upper GI Series with Air and High-Density Barium

    CPT-74248-SMALL-INTESTINE-FOLLOW-THROUGH-AFTER-UPPER-GASTROINTESTINAL-STUDY

    CPT 74248: Small Intestine Follow-Through, Multiple Series

    CPT-74250-SMALL-BOWEL-SINGLE-CONTRAST-BARIUM-STUDY

    CPT 74250: Small Bowel Single‑Contrast Barium Study

    CPT-74261-CT-COLONOGRAPHY-NO-CONTRAST

    CPT 74261: CT Colon, Non-Contrast

    Showing 1–10 of 25

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.