CPT code 65110 identifies unilateral orbital exenteration, the surgical removal of the eye socket contents performed for severe trauma, extensive infection, or ocular neoplasm. The code captures a high-acuity, typically inpatient or major ambulatory procedural service with significant clinical and financial implications due to its complexity and postoperative needs. Nationally, services represented by this code intersect surgical specialties including ophthalmology, otolaryngology, and craniofacial surgery and can affect hospital resource use, case mix, and payer reimbursement policies.

Key payers included in this analysis are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the code’s clinical scope, typical sites of service, and where it fits within surgical service lines. The publication outlines common billing considerations, relevant modifiers (listed elsewhere), and expected documentation elements. It also highlights benchmarks and policy topics that influence coverage and payment for high-acuity ophthalmic surgeries at a national level.

This executive summary prepares clinicians, coders, and payers to understand the clinical context of 65110, the operational settings where it is used, and the types of analyses and policy updates covered in the full publication. Data not available in the input is noted where applicable in detailed sections.