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    v1.0.30
    OpenPayerBilling CodesDestruction by Neurolytic Agent (eg, Chemical, Thermal, Electrical or Radiofrequency) Procedures on the Somatic NervesCPT cpt-64632-neurolysis-nerve-destruction-for-pain
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    CPT 64632: Neurolysis (Nerve Destruction)

    Medicare pays $93 on average nationally for this procedure.

    CPT code 64632 describes neurolysis, the targeted destruction of pain-carrying nerves using chemical agents, heat, or radiofrequency techniques, performed as an interventional pain procedure; the service typically involves percutaneous or image-guided nerve ablation and is commonly provided in an ambulatory surgery center or hospital outpatient setting for diagnostic or therapeutic pain relief.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient with chronic, refractory thoracic radicular pain after prior conservative care presents to an outpatient interventional pain clinic for targeted neurolysis using radiofrequency ablation. The patient has focal neuropathic pain localized to the right T6 dermatome with prior diagnostic medial branch blocks demonstrating temporary relief. After informed consent and verification of no contraindications, the patient is positioned on the procedure table, monitored with ECG, pulse oximetry, and blood pressure, and intravenous access is established. Under fluoroscopic guidance and sterile technique, the physician advances a radiofrequency needle to the targeted dorsal rami/medial branch nerve and confirms position with sensory and motor stimulation. Thermal radiofrequency neurolysis is performed to coagulate the nerve for sustained pain relief. The patient is observed in recovery for hemodynamic stability and discharged with post-procedure instructions and a plan for follow-up.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    64483Injection(s), anesthetic agent and/or steroid, transforaminal epidural; lumbar or sacral, single levelOften performed before or instead of neurolysis for radicular pain diagnostic or therapeutic purposes; may precede neurolysis to identify pain generator.
    64635Destruction by neurolytic agent; other peripheral nerve(s) (eg, stellate ganglion, other sympathetic)Alternative neurolytic technique for different nerve targets; related when sympathetic or peripheral neurolysis is indicated instead of dorsal rami/medial branch.
    61782Stereotactic ablation, any method, single or multiple sessions, deep brain (including stereotactic mapping)Not typically performed with 64632 but represents advanced lesioning techniques; included for comprehensive workflow where lesioning therapies are considered.
    99284Emergency department visit, moderate to high severityMay be billed if patient presents emergently with procedure-related issues requiring evaluation prior to or after neurolysis.
    77002Fluoroscopic guidance for needle placement (radiologic supervision and interpretation)Imaging guidance frequently documented and billed by the facility or radiology service to support needle localization during radiofrequency neurolysis.

    Related Modifiers

    11 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Showing 1–10 of 11

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    207L00000X
    342000000X
    261QM1102X
    251C00000X
    273100000X
    310500000X
    111NI0900X

    Related ICD-10-CM Codes

    17 rows

    ICD-10-CM CodeDescription
    B86Scabies
    G89.0Central pain syndrome
    G89.3Neoplasm related pain (acute) (chronic)
    G89.4Chronic pain syndrome
    I73.9Peripheral vascular disease, unspecified
    M47.12Other spondylosis with myelopathy, cervical region
    M47.21Other spondylosis with radiculopathy, occipito-atlanto-axial region
    M51.26Other intervertebral disc displacement, lumbar region
    M51.27Other intervertebral disc displacement, lumbosacral region
    M54.12Radiculopathy, cervical region

    Showing 1–10 of 17

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-64600-TRIGEMINAL-NERVE-NEURODESTRUCTIVE-INJECTION

    CPT 64600: Trigeminal Nerve Neurodestruction by Injection

    CPT-64605-TRIGEMINAL-NERVE-NEURODESTRUCTIVE-INJECTION

    CPT 64605: Trigeminal Nerve Neurodestructive Injection

    CPT-64610-TRIGEMINAL-NERVE-NEURODESTRUCTIVE-INJECTION

    CPT 64610: Trigeminal Nerve Neurodestructive Injection

    CPT-64611-SALIVARY-GLAND-CHEMICAL-DENERVATION-BILATERAL

    CPT 64611: Bilateral Salivary Gland Chemical Injection for Sialorrhea

    CPT-64612-FACIAL-NERVE-CHEMICAL-NEUROLYSIS-UNILATERAL

    CPT 64612: Facial Nerve Chemical Neurolysis, Unilateral

    CPT-64615-BILATERAL-CHEMICAL-DENERVATION-FACIAL-CERVICAL-MUSCLES

    CPT 64615: Bilateral Chemical Denervation of Head and Neck Muscles

    CPT-64616-UNILATERAL-CERVICAL-MUSCLE-CHEMICAL-DENERVATION

    CPT 64616: Unilateral Neck Muscle Chemodenervation

    CPT-64617-PERCUTANEOUS-LARYNGEAL-CHEMODENERVATION-UNILATERAL

    CPT 64617: Percutaneous Chemodenervation of Larynx, Unilateral

    CPT-64620-INTERCOSTAL-NERVE-ABLATION

    CPT 64620: Intercostal Nerve Destruction (Chemical/Heat/Radiofrequency)

    CPT-64624-GENICULAR-NERVE-NEUROLYSIS-KNEE

    CPT 64624: Genicular Nerve Neurolysis for Knee Pain

    Showing 1–10 of 26

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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