CPT code 64582 covers open surgical implantation of a hypoglossal nerve neurostimulator electrode array with implantation of a programmable pulse generator and one or more distal respiratory sensor electrodes. This implantable neurostimulation system is used to manage obstructive sleep apnea by restoring or maintaining airway patency through targeted tongue muscle activation. The procedure is clinically significant as an alternative for patients who are intolerant of or unresponsive to positive airway pressure therapy, and it has implications for surgical, anesthesia, and device coverage policies across payers.

Key payers considered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise review of the clinical purpose and typical care setting for the procedure, plus national-level payer coverage considerations, common modifier usage, and benchmarking context where available. The publication outlines typical sites of service, service type, and the core clinical rationale, and it flags areas where data were not provided in the input. Intended audiences include billing and coding professionals, surgical and sleep medicine clinicians, and payer policy analysts seeking an authoritative, national-level summary of the code and its clinical use.