CPT code 61533 covers a neurosurgical procedure that elevates a portion of the skull and places a subdural electrode array beneath the dura mater for invasive seizure monitoring. This procedure is a critical diagnostic step for patients with medically refractory epilepsy when noninvasive modalities fail to localize seizure onset. Nationally, the code represents high-complexity operative neurosurgery with implications for hospital resource use, perioperative risk management, and care coordination across neurology and neurosurgery teams. Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context, typical sites of service, common billing modifiers, and the payer mix addressed in the publication. The report also summarizes reimbursement and utilization benchmarks where available, highlights relevant policy considerations affecting coverage for invasive monitoring, and provides coding and billing nuances specific to intracranial electrode placement. Data not available in the input is noted where applicable; clinical descriptions focus on the procedure’s diagnostic role in epilepsy management and its operational setting in hospital-based neurosurgical care.