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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the Parathyroid, Thymus, Adrenal Glands, Pancreas, and Carotid BodyCPT cpt-60545-adrenal-exploration-removal-adrenalectomy
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    CPT 60545: Adrenal Gland Exploration or Removal

    Medicare pays $1185 on average nationally for this procedure.

    CPT code 60545 describes surgical exploration or removal of one or both adrenal glands, including biopsy when performed, and covers open, laparoscopic, or other operative approaches for treatment of overactive glands, benign or malignant adrenal tumors, or adrenal disease; service type: adrenalectomy / adrenal exploration surgery; typical site of service: inpatient or outpatient hospital operating room or ambulatory surgical center.

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient presents with episodic hypertension, headaches, and biochemical testing consistent with catecholamine excess. Imaging (CT or MRI) identifies a 3.5 cm mass in the right adrenal gland suspicious for pheochromocytoma. After endocrinology-guided preoperative optimization (alpha-then beta-blockade) and informed consent, the patient is scheduled for a right adrenalectomy. The surgical team performs a laparoscopic lateral transabdominal approach with intraoperative ultrasound localization and removal of the adrenal gland. Frozen section or targeted biopsy may be performed if margins or unexpected pathology are encountered. Typical perioperative workflow includes preoperative imaging and labs, anesthesia evaluation, intraoperative monitoring of hemodynamics, specimen submission to pathology, postoperative monitoring for hemodynamic instability and adrenal insufficiency, and endocrinology follow-up for hormone replacement if bilateral disease or functional loss occurs.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    49329Laparoscopy, surgical; diagnostic, with or without collection of specimen(s) by biopsyMay be used when a diagnostic laparoscopic exploration or biopsy is performed prior to or instead of formal adrenalectomy
    60540Partial adrenalectomy, unilateralUsed when only a portion of an adrenal gland is excised rather than complete adrenalectomy
    76942Ultrasonic guidance for needle placement (e.g., for biopsy)Used intraoperatively or preoperatively to guide adrenal biopsy or localization
    88305Level IV surgical pathology, gross and microscopic examinationTypical for examination of adrenalectomy specimens sent to pathology
    32601Thoracoscopy, surgical; with total or partial lobectomy (open thoracic procedures example)Listed when a thoracic approach is needed for ectopic or difficult adrenal lesions (rarely applicable)
    43280Laparoscopy, surgical, with esophagogastrectomy (example complex abdominal procedure)May be reported when combined complex abdominal procedures are performed with adrenalectomy (useful for multiple concurrent operations)

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208100000X
    207P00000X
    208000000X
    333600000X
    222Q00000X
    2086S0102X
    163WA2000X
    2471R0002X

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-60500-PARATHYROID-EXPLORATION-PARATHYROIDECTOMY

    CPT 60500: Parathyroid Exploration and Parathyroidectomy

    CPT-60502-PARATHYROIDECTOMY-EXCISION-PARATHYROID-GLAND

    CPT 60502: Parathyroidectomy, Removal of One or More Parathyroid Glands

    CPT-60505-PARATHYROID-GLAND-EXCISION-OR-EXPLORATION

    CPT 60505: Parathyroid Exploration or Resection

    CPT-60512-PARATHYROID-AUTOTRANSPLANTATION-DURING-THYROID-OR-PARATHYROID-SURGERY

    CPT 60512: Parathyroid Autotransplantation into Muscle Pocket

    CPT-60520-THYMECTOMY-THYMUS-GLAND-RESECTION

    CPT 60520: Thymectomy, Partial or Total

    CPT-60521-THYMECTOMY-PARTIAL-OR-TOTAL-FOR-THYMOMA

    CPT 60521: Partial or Total Thymectomy

    CPT-60522-THYMECTOMY-OPEN-STERNOTOMY-THORACOTOMY

    CPT 60522: Thymectomy via Sternotomy or Thoracotomy

    CPT-60540-ADRENAL-EXPLORATION-OR-REMOVAL-ADRENALECTOMY-FOR-MALIGNANCY

    CPT 60540: Exploration or Removal of Adrenal Gland(s)

    CPT-60600-CAROTID-BODY-TUMOR-EXCISION

    CPT 60600: Carotid Body Tumor Resection, Bifurcation

    CPT-60605-CAROTID-BODY-TUMOR-EXCISION-WITH-CAROTID-ARTERY-RESECTION

    CPT 60605: Carotid Body Tumor Resection with Carotid Excision

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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