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    OpenPayerBilling CodesExcision Procedures on the Parathyroid, Thymus, Adrenal Glands, Pancreas, and Carotid BodyCPT cpt-60521-thymectomy-partial-or-total-for-thymoma
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    CPT 60521: Partial or Total Thymectomy

    Medicare pays $1090 on average nationally for this procedure.

    CPT code 60521 describes a surgical thymectomy in which part or all of the thymus gland is removed without excision of adjacent structures; the service is a surgical excision typically performed in an inpatient or outpatient surgical setting via open chest or mediastinal approach for management of a thymoma or other thymic pathology.

    For related coverage guidance, see recent payer policy updates: Diabetic Supplies, Radiofrequency Ablation for Thyroid Nodules, Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 56-year-old patient presents with an anterior mediastinal mass discovered on chest imaging after progressive chest discomfort and fatigue. Cross-sectional imaging (CT or MRI) demonstrates a well-circumscribed lesion consistent with a thymoma without invasion of adjacent structures. Preoperative workup includes pulmonary function testing, cardiopulmonary evaluation, and oncologic staging. The thoracic surgeon schedules a transcervical or partial upper median sternotomy approach for a thymectomy limited to the thymus gland, CPT 60521, with general endotracheal anesthesia. Intraoperative steps include median cervical incision (or small upper sternotomy), dissection and mobilization of the thymus, hemostasis, and removal of thymic tissue with sending specimens for pathology. Postoperative workflow includes recovery in PACU, chest radiograph as indicated, pain control, wound care, pathology review, and follow-up in thoracic surgery and oncology as needed for staging and adjuvant therapy decisions.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    19307Partial or complete mastectomy, simpleData not available in the input.
    31628Thoracoscopy; diagnostic, with or without pleural biopsyUsed for diagnostic evaluation or biopsy of mediastinal/pleural disease prior to or instead of open thymectomy.
    32551Tube thoracostomy, includes water seal (e.g., chest tube)May be performed postoperatively if pleural drainage is required after mediastinal surgery.
    43281Esophagoscopy, flexible, transoral; operative, with biopsyData not available in the input.
    60521Excision, thymus, partial or totalPrimary procedure code for removal of the thymus without adjacent structures; represents the index operation described.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2080P0207X
    207RH0000X
    2084P0800X
    207L00000X
    207QH0002X
    146D00000X
    2083B0002X
    1744P3200X

    Related ICD-10-CM Codes

    18 rows

    ICD-10-CM CodeDescription
    C34.90Malignant neoplasm of unspecified part of unspecified bronchus or lung
    D15.0Benign neoplasm of thymus
    D15.1Benign neoplasm of heart
    D38.1Neoplasm of uncertain behavior of trachea, bronchus and lung
    D49.1Neoplasm of unspecified behavior of respiratory system
    D86.9Sarcoidosis, unspecified
    D89.1Cryoglobulinemia
    E27.1Primary adrenocortical insufficiency
    J95.2Acute pulmonary insufficiency following nonthoracic surgery
    J98.4Other disorders of lung

    Showing 1–10 of 18

    Related Payer Policy Updates

    Specialty: Endocrinology1 / 3

    10 rows

    PolicyPayerEffective Date
    Diabetic SuppliesCigna2026-10-15
    Radiofrequency Ablation for Thyroid NodulesCigna2026-10-15
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Idaho Only)UnitedHealthcare2026-10-01
    Tzield (teplizumab-mzwv) CoverageUnitedHealthcare2026-10-01
    Continuous Glucose Monitoring and Insulin Delivery for Managing Diabetes (for Indiana Only)UnitedHealthcare2026-10-01
    Medical Necessity Guidelines Insulin PumpsMass General Brigham Health Plan2026-10-01
    Medical Necessity Guidelines: Continuous Glucose MonitorsMass General Brigham Health Plan2026-10-01
    Continuous Glucose MonitoringAmbetter Nevada2026-10-01
    Salivary Hormone TestingOscar Health2026-10-01
    Bone Turnover Markers TestingOscar Health2026-10-01

    Related Codes

    CPT-60500-PARATHYROID-EXPLORATION-PARATHYROIDECTOMY

    CPT 60500: Parathyroid Exploration and Parathyroidectomy

    CPT-60502-PARATHYROIDECTOMY-EXCISION-PARATHYROID-GLAND

    CPT 60502: Parathyroidectomy, Removal of One or More Parathyroid Glands

    CPT-60505-PARATHYROID-GLAND-EXCISION-OR-EXPLORATION

    CPT 60505: Parathyroid Exploration or Resection

    CPT-60512-PARATHYROID-AUTOTRANSPLANTATION-DURING-THYROID-OR-PARATHYROID-SURGERY

    CPT 60512: Parathyroid Autotransplantation into Muscle Pocket

    CPT-60520-THYMECTOMY-THYMUS-GLAND-RESECTION

    CPT 60520: Thymectomy, Partial or Total

    CPT-60522-THYMECTOMY-OPEN-STERNOTOMY-THORACOTOMY

    CPT 60522: Thymectomy via Sternotomy or Thoracotomy

    CPT-60540-ADRENAL-EXPLORATION-OR-REMOVAL-ADRENALECTOMY-FOR-MALIGNANCY

    CPT 60540: Exploration or Removal of Adrenal Gland(s)

    CPT-60545-ADRENAL-EXPLORATION-REMOVAL-ADRENALECTOMY

    CPT 60545: Adrenal Gland Exploration or Removal

    CPT-60600-CAROTID-BODY-TUMOR-EXCISION

    CPT 60600: Carotid Body Tumor Resection, Bifurcation

    CPT-60605-CAROTID-BODY-TUMOR-EXCISION-WITH-CAROTID-ARTERY-RESECTION

    CPT 60605: Carotid Body Tumor Resection with Carotid Excision

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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