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    v1.0.30
    OpenPayerBilling CodesOther Procedures on the ProstateCPT cpt-55881-transurethral-ultrasound-ablation-prostate-mri-guided
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    CPT 55881: Transurethral Ultrasound Ablation of Prostate Tissue, MRI-Guided

    Medicare pays $9708 on average nationally for this procedure.

    CPT code 55881 describes transurethral ultrasound ablation (TULSA) of prostate tissue using a transducer previously inserted in the urethra with magnetic resonance imaging guidance; this is an image-guided prostate ablation procedure (minimally invasive thermal ablation) typically performed by urology or interventional radiology teams in an outpatient surgical center or hospital operating room with MRI capability.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 65-year-old man with symptomatic benign prostatic hyperplasia (BPH) or localized prostate cancer who has persistent lower urinary tract symptoms or focal prostate malignancy despite medical therapy and who prefers a minimally invasive, gland-preserving option. The patient undergoes pre-procedure evaluation including history and physical, prostate-specific antigen (PSA) testing, urinary flow rate measurement, and prostate imaging (multiparametric MRI). On the day of service the patient is brought to an MRI suite equipped for interventional procedures. Under conscious sedation or monitored anesthesia care, a transrectal or transurethral device (transducer) is placed in the urethra and positioned within the prostate under MRI visualization. The interventional urologist or radiologist performs real-time MRI-guided transurethral ultrasound ablation (TULSA) to target and thermally ablate prostatic tissue while monitoring temperature and anatomic boundaries on MRI sequences. Post-ablation MRI scans confirm the treated zone. The patient is recovered in a post-anesthesia area, receives short-term catheter drainage as indicated, and is discharged with follow-up plans for PSA surveillance, symptom assessment, and imaging as clinically warranted.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    55866Transurethral resection of the prostate (TURP), retropubic, total or subtotalAlternative or prior endoscopic therapy for obstructive BPH; may be a comparative or preceding intervention in workflow decisions.
    52601Transurethral resection of prostate, including control of post-operative bleeding, completeHistorical/alternative transurethral surgical approach for BPH symptom relief; not performed concurrently but considered in treatment planning.
    52287Cystourethroscopy, with biopsy(s) of bladder and/or urethraDiagnostic endoscopic evaluation that may be performed pre-procedure to evaluate concurrent bladder pathology.
    77021Magnetic resonance guidance for interventional procedure, all systems, with placement of radiation therapy deviceRelated MRI-guidance/registration codes; used for MRI-guided interventional procedures to document imaging guidance.
    55866(duplicate listed above)(duplicate entry removed in use; see first 55866)

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208800000X
    207T00000X
    208VP0000X
    2471V0105X
    146D00000X
    103TR0400X
    207ND0900X
    163WM0102X

    Related ICD-10-CM Codes

    23 rows

    ICD-10-CM CodeDescription
    C61Malignant neoplasm of prostate
    D40.0Neoplasm of uncertain behavior of prostate
    N10Acute pyelonephritis
    N12Tubulo-interstitial nephritis, not specified as acute or chronic
    N20.0Calculus of kidney
    N20.1Calculus of ureter
    N21.0Calculus in bladder
    N21.1Calculus in urethra
    N40.0Benign prostatic hyperplasia without lower urinary tract symptoms
    N40.1Benign prostatic hyperplasia with lower urinary tract symptoms

    Showing 1–10 of 23

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-55870-EJACULATORY-STIMULATION-AND-SEMEN-COLLECTION

    CPT 55870: Electrical Ejaculation and Semen Collection

    CPT-55873-PROSTATE-CRYOABLATION-ULTRASOUND-GUIDED

    CPT 55873: Prostate Cryoablation Under Ultrasound Guidance

    CPT-55874-PROSTATE-BIODEGRADABLE-SPACE-INJECTION-IMAGE-GUIDED

    CPT 55874: Perineal Image-Guided Biodegradable Prostate-Rectum Spacer Insertion

    CPT-55875-PROSTATE-SEED-IMPLANTATION-BRACHYTHERAPY-NEEDLE-PLACEMENT

    CPT 55875: Prostate Needle/Catheter Placement for Seed Implantation

    CPT-55876-PROSTATE-FIDUCIAL-MARKER-PLACEMENT-FOR-RADIOTHERAPY

    CPT 55876: Prostate Placement of Radiation Markers or Dosimeters

    CPT-55877-PROSTATE-IRE-ABLATION-PERCUTANEOUS

    CPT 55877: Prostate Irreversible Electroporation (Percutaneous Ablation)

    CPT-55880-TRANSRECTAL-HIFU-PROSTATE-ABLATION

    CPT 55880: Transrectal HIFU Ablation of Prostate Malignancy

    CPT-55882-TRANSURETHRAL-ULTRASOUND-ABLATION-PROSTATE-MRI-GUIDED

    CPT 55882: Transurethral Ultrasound Ablation of Prostate Tissue

    CPT-55899-MALE-GENITAL-SYSTEM-UNLISTED-PROCEDURE

    CPT 55899: Unlisted Procedure, Male Genital System

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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