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    v1.0.30
    OpenPayerBilling CodesOther Procedures on the ProstateCPT cpt-55877-prostate-ire-ablation-percutaneous
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    CPT 55877: Prostate Irreversible Electroporation (Percutaneous Ablation)

    Medicare pays $683 on average nationally for this procedure.

    CPT code 55877 describes percutaneous irreversible electroporation (IRE) ablation of one or more prostate tumors, a minimally invasive image-guided tumor ablation procedure in which a probe is inserted through the skin into the prostate and delivers very short, high-voltage electrical pulses to permanently disrupt tumor cell membranes and cause tumor cell death without thermal energy; service type: image-guided percutaneous tumor ablation; typical site of service: outpatient interventional radiology suite or ambulatory surgical center.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 65-year-old man with localized, biopsy-proven prostate carcinoma confined to the gland who elects focal tumor ablation. He presents after multiparametric MRI and targeted biopsy confirm one or more discrete tumor foci suitable for a percutaneous approach. Pre-procedure assessment includes medical clearance, coagulation review, and review of prior imaging (MRI/ultrasound). On the day of service, the patient receives conscious sedation or general anesthesia in an outpatient procedural suite or ambulatory surgery center. Under transrectal or transperineal ultrasound and/or CT/MRI fusion guidance, the interventional urology or interventional radiology team inserts one or more probes percutaneously into the prostate tumor(s). The device delivers irreversible electroporation (IRE) electrical pulses to ablate tumor cells while preserving surrounding structures. Intra-procedural imaging guidance and neurovascular bundle assessment are performed. Post-procedure, the patient is observed for urinary retention, hematuria, and pain, receives discharge instructions, and returns for follow-up PSA monitoring and imaging as indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    55877Ablation, one or more prostate tumors, irreversible electroporation (IRE), percutaneous, includes imaging guidancePrimary procedure code describing percutaneous IRE prostate tumor ablation with imaging guidance.

    76872 | Ultrasound, transrectal; with imaging documentation and guidance for needle placement | Commonly used for real-time transrectal ultrasound guidance and needle/probe placement during percutaneous prostate ablation.

    77012 | CT guidance for needle placement (eg, biopsy, aspiration, injection, localization device), radiological supervision and interpretation | Used when CT guidance is employed for probe placement during percutaneous IRE.

    95978 | Electronic analysis of implanted neurostimulator pulse generator or receiver (Not directly for IRE) | Data not commonly applicable; Data not available in the input.

    99152 | Moderate sedation services provided by the physician performing the procedure (for initial 15–30 minutes) | Used when the operating physician provides moderate sedation during the IRE procedure; document separately per payor rules.

    Related Modifiers

    5 rows

    ModifierDescriptionWhen to Use
    25CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207V00000X
    364S00000X
    208000000X
    363L00000X
    3416S0300X
    3336N0007X
    225200000X
    207ZC0500X

    Related ICD-10-CM Codes

    26 rows

    ICD-10-CM CodeDescription
    C61Malignant neoplasm of prostate
    C79.11Secondary malignant neoplasm of bladder
    D07.5Carcinoma in situ of prostate
    D29.1Benign neoplasm of prostate
    D40.0Neoplasm of uncertain behavior of prostate
    D41.4Neoplasm of uncertain behavior of bladder
    N13.6Pyonephrosis
    N32.0Bladder-neck obstruction
    N32.89Other specified disorders of bladder
    N40.0Benign prostatic hyperplasia without lower urinary tract symptoms

    Showing 1–10 of 26

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-55870-EJACULATORY-STIMULATION-AND-SEMEN-COLLECTION

    CPT 55870: Electrical Ejaculation and Semen Collection

    CPT-55873-PROSTATE-CRYOABLATION-ULTRASOUND-GUIDED

    CPT 55873: Prostate Cryoablation Under Ultrasound Guidance

    CPT-55874-PROSTATE-BIODEGRADABLE-SPACE-INJECTION-IMAGE-GUIDED

    CPT 55874: Perineal Image-Guided Biodegradable Prostate-Rectum Spacer Insertion

    CPT-55875-PROSTATE-SEED-IMPLANTATION-BRACHYTHERAPY-NEEDLE-PLACEMENT

    CPT 55875: Prostate Needle/Catheter Placement for Seed Implantation

    CPT-55876-PROSTATE-FIDUCIAL-MARKER-PLACEMENT-FOR-RADIOTHERAPY

    CPT 55876: Prostate Placement of Radiation Markers or Dosimeters

    CPT-55880-TRANSRECTAL-HIFU-PROSTATE-ABLATION

    CPT 55880: Transrectal HIFU Ablation of Prostate Malignancy

    CPT-55881-TRANSURETHRAL-ULTRASOUND-ABLATION-PROSTATE-MRI-GUIDED

    CPT 55881: Transurethral Ultrasound Ablation of Prostate Tissue, MRI-Guided

    CPT-55882-TRANSURETHRAL-ULTRASOUND-ABLATION-PROSTATE-MRI-GUIDED

    CPT 55882: Transurethral Ultrasound Ablation of Prostate Tissue

    CPT-55899-MALE-GENITAL-SYSTEM-UNLISTED-PROCEDURE

    CPT 55899: Unlisted Procedure, Male Genital System

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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