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    v1.0.30
    OpenPayerBilling CodesOther Procedures on the ProstateCPT cpt-55880-transrectal-hifu-prostate-ablation
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    CPT 55880: Transrectal HIFU Ablation of Prostate Malignancy

    Medicare pays $895 on average nationally for this procedure.

    CPT code 55880 describes transrectal high intensity–focused ultrasound (HIFU) ablation of malignant prostate tissue under ultrasound guidance, a minimally invasive therapeutic procedure performed by a urologist using a rectally inserted HIFU device; service type: image-guided prostate ablation/thermal therapy; typical site of service: outpatient surgical center or hospital operating room with ultrasound guidance.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 69-year-old male with biopsy-proven localized prostate adenocarcinoma (Gleason 3+4), rising PSA despite prior active surveillance, is scheduled for focal high intensity–focused ultrasound treatment. The patient presents to an outpatient ambulatory surgical center or hospital-based operating room. Pre-procedure workflow includes informed consent, pre-op anesthesia evaluation (general or spinal anesthesia), ultrasound imaging for target localization, and transrectal insertion of the HIFU device. The provider uses real-time ultrasound guidance to deliver focused thermal energy to ablate malignant prostate tissue while monitoring surrounding structures. Post-procedure workflow includes recovery in PACU, immediate assessment for urinary retention and rectal bleeding, catheter placement as needed, discharge instructions, and scheduled follow-up with PSA testing and repeat imaging or biopsy as clinically indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    51701Insertion of temporary indwelling urethral catheter; simple (e.g., straight catheterization)Often performed before or after HIFU for urinary drainage or retention management
    55866Laparoscopic radical prostatectomyAlternative definitive surgical treatment for localized prostate cancer; may be considered in treatment planning
    76942Ultrasonic guidance for needle placement (e.g., diagnostic or therapeutic)Represents ultrasound guidance procedures; intra-procedural ultrasound guidance is intrinsic to 55880
    52000Cystourethroscopy, diagnostic, with or without collection of specimen(s) by brushing or washingMay be performed if hematuria or urethral concern arises peri-procedurally
    99223Initial hospital care, typically 70 minutes or more, per day, for the evaluation and management of a patientExample of an E/M service that may be billed for hospital admissions related to complications

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    79Modifier 79 indicates a surgical procedure performed during the postoperative global period of a prior surgery that is unrelated to the original procedure. Per AMA/CPT and CMS guidance, it is…- Use modifier 79 when the same physician (or same‑specialty physician in the same group) performs a surgical procedure during the postoperative global period of a prior surgery and the new procedure…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    363A00000X
    207RH0000X
    207L00000X
    363LF0000X
    208800000X
    163WN1003X
    282J00000X
    331L00000X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-55870-EJACULATORY-STIMULATION-AND-SEMEN-COLLECTION

    CPT 55870: Electrical Ejaculation and Semen Collection

    CPT-55873-PROSTATE-CRYOABLATION-ULTRASOUND-GUIDED

    CPT 55873: Prostate Cryoablation Under Ultrasound Guidance

    CPT-55874-PROSTATE-BIODEGRADABLE-SPACE-INJECTION-IMAGE-GUIDED

    CPT 55874: Perineal Image-Guided Biodegradable Prostate-Rectum Spacer Insertion

    CPT-55875-PROSTATE-SEED-IMPLANTATION-BRACHYTHERAPY-NEEDLE-PLACEMENT

    CPT 55875: Prostate Needle/Catheter Placement for Seed Implantation

    CPT-55876-PROSTATE-FIDUCIAL-MARKER-PLACEMENT-FOR-RADIOTHERAPY

    CPT 55876: Prostate Placement of Radiation Markers or Dosimeters

    CPT-55877-PROSTATE-IRE-ABLATION-PERCUTANEOUS

    CPT 55877: Prostate Irreversible Electroporation (Percutaneous Ablation)

    CPT-55881-TRANSURETHRAL-ULTRASOUND-ABLATION-PROSTATE-MRI-GUIDED

    CPT 55881: Transurethral Ultrasound Ablation of Prostate Tissue, MRI-Guided

    CPT-55882-TRANSURETHRAL-ULTRASOUND-ABLATION-PROSTATE-MRI-GUIDED

    CPT 55882: Transurethral Ultrasound Ablation of Prostate Tissue

    CPT-55899-MALE-GENITAL-SYSTEM-UNLISTED-PROCEDURE

    CPT 55899: Unlisted Procedure, Male Genital System

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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